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Low-dose Btk inhibitors selectively block platelet activation by CLEC-2.
Nicolson PLR, Nock SH, Hinds J, Garcia-Quintanilla L, Smith CW, Campos J, Brill A, Pike JA, Khan AO, Poulter NS, Kavanagh DM, Watson S, Watson CN, Clifford H, Huissoon AP, Pollitt AY, Eble JA, Pratt G, Watson SP, Hughes CE. Nicolson PLR, et al. Among authors: watson cn, watson sp, watson s. Haematologica. 2021 Jan 1;106(1):208-219. doi: 10.3324/haematol.2019.218545. Haematologica. 2021. PMID: 31949019 Free PMC article.
A novel Syk-dependent mechanism of platelet activation by the C-type lectin receptor CLEC-2.
Suzuki-Inoue K, Fuller GL, García A, Eble JA, Pöhlmann S, Inoue O, Gartner TK, Hughan SC, Pearce AC, Laing GD, Theakston RD, Schweighoffer E, Zitzmann N, Morita T, Tybulewicz VL, Ozaki Y, Watson SP. Suzuki-Inoue K, et al. Among authors: watson sp. Blood. 2006 Jan 15;107(2):542-9. doi: 10.1182/blood-2005-05-1994. Epub 2005 Sep 20. Blood. 2006. PMID: 16174766 Free article.
Involvement of Src kinases and PLCgamma2 in clot retraction.
Suzuki-Inoue K, Hughes CE, Inoue O, Kaneko M, Cuyun-Lira O, Takafuta T, Watson SP, Ozaki Y. Suzuki-Inoue K, et al. Thromb Res. 2007;120(2):251-8. doi: 10.1016/j.thromres.2006.09.003. Epub 2006 Oct 19. Thromb Res. 2007. PMID: 17055557 Free PMC article.
Minimal regulation of platelet activity by PECAM-1.
Dhanjal TS, Ross EA, Auger JM, McCarty OJ, Hughes CE, Senis YA, Buckley CD, Watson SP. Dhanjal TS, et al. Among authors: watson sp. Platelets. 2007 Feb;18(1):56-67. doi: 10.1080/09537100600881396. Platelets. 2007. PMID: 17365855 Free PMC article.
Renal cells activate the platelet receptor CLEC-2 through podoplanin.
Christou CM, Pearce AC, Watson AA, Mistry AR, Pollitt AY, Fenton-May AE, Johnson LA, Jackson DG, Watson SP, O'Callaghan CA. Christou CM, et al. Biochem J. 2008 Apr 1;411(1):133-40. doi: 10.1042/BJ20071216. Biochem J. 2008. PMID: 18215137 Free PMC article.
3,295 results