Lam Y - Search Results

1

Antimalarial N ¹,N ³-Dialkyldioxonaphthoimidazoliums: Synthesis, Biological Activity, and Structure-activity Relationships.

Ahenkorah S, Coertzen D, Tong JX, Fridianto K, Wittlin S, Birkholtz LM, Tan KSW, Lam Y, Go ML, Haynes RK. Ahenkorah S, et al. Among authors: lam y. ACS Med Chem Lett. 2019 Dec 11;11(1):49-55. doi: 10.1021/acsmedchemlett.9b00457. eCollection 2020 Jan 9. ACS Med Chem Lett. 2019. PMID: 31938463 Free PMC article.

2

Galloyl esters of trans-stilbenes are inhibitors of FASN with anticancer activity on non-small cell lung cancer cells.

Tan YJ, Ali A, Tee SY, Teo JT, Xi Y, Go ML, Lam Y. Tan YJ, et al. Among authors: lam y. Eur J Med Chem. 2019 Nov 15;182:111597. doi: 10.1016/j.ejmech.2019.111597. Epub 2019 Aug 6. Eur J Med Chem. 2019. PMID: 31422225

3

Amide-Amine Replacement in Indole-2-carboxamides Yields Potent Mycobactericidal Agents with Improved Water Solubility.

Tan YJ, Li M, Gunawan GA, Nyantakyi SA, Dick T, Go ML, Lam Y. Tan YJ, et al. Among authors: lam y. ACS Med Chem Lett. 2020 Nov 16;12(5):704-712. doi: 10.1021/acsmedchemlett.0c00588. eCollection 2021 May 13. ACS Med Chem Lett. 2020. PMID: 34055215 Free PMC article.

4

Functionalized Dioxonaphthoimidazoliums: A Redox Cycling Chemotype with Potent Bactericidal Activities against Mycobacterium tuberculosis.

Fridianto KT, Li M, Hards K, Negatu DA, Cook GM, Dick T, Lam Y, Go ML. Fridianto KT, et al. Among authors: lam y. J Med Chem. 2021 Nov 11;64(21):15991-16007. doi: 10.1021/acs.jmedchem.1c01383. Epub 2021 Oct 27. J Med Chem. 2021. PMID: 34706190 Free PMC article.

5

Alkyltriphenylphosphonium turns naphthoquinoneimidazoles into potent membrane depolarizers against mycobacteria.

Fridianto KT, Gunawan GA, Hards K, Sarathy JP, Cook GM, Dick T, Go ML, Lam Y. Fridianto KT, et al. Among authors: lam y. RSC Med Chem. 2022 Oct 13;13(12):1605-1613. doi: 10.1039/d2md00251e. eCollection 2022 Dec 14. RSC Med Chem. 2022. PMID: 36545436 Free PMC article.

6

Development of fluorous boronic acid catalysts integrated with sulfur for enhanced amidation efficiency.

Fridianto KT, Wen YP, Lo LC, Lam Y. Fridianto KT, et al. Among authors: lam y. RSC Adv. 2023 Jun 9;13(25):17420-17426. doi: 10.1039/d3ra03300g. eCollection 2023 Jun 5. RSC Adv. 2023. PMID: 37304775 Free PMC article.

7

Synthesis and evaluation of sphingosine analogues as inhibitors of sphingosine kinases.

Wong L, Tan SS, Lam Y, Melendez AJ. Wong L, et al. Among authors: lam y. J Med Chem. 2009 Jun 25;52(12):3618-26. doi: 10.1021/jm900121d. J Med Chem. 2009. PMID: 19469544

8

Synthesis and disulfide bond connectivity-activity studies of a kalata B1-inspired cyclopeptide against dengue NS2B-NS3 protease.

Gao Y, Cui T, Lam Y. Gao Y, et al. Among authors: lam y. Bioorg Med Chem. 2010 Feb;18(3):1331-6. doi: 10.1016/j.bmc.2009.12.026. Epub 2009 Dec 29. Bioorg Med Chem. 2010. PMID: 20042339

9

Synthesis and biological evaluation of polyenylpyrrole derivatives as anticancer agents acting through caspases-dependent apoptosis.

Fang Z, Liao PC, Yang YL, Yang FL, Chen YL, Lam Y, Hua KF, Wu SH. Fang Z, et al. Among authors: lam y. J Med Chem. 2010 Nov 25;53(22):7967-78. doi: 10.1021/jm100619x. Epub 2010 Oct 22. J Med Chem. 2010. PMID: 20964408

10

Synthesis of cyclic di-nucleotidic acids as potential inhibitors targeting diguanylate cyclase.

Ching SM, Tan WJ, Chua KL, Lam Y. Ching SM, et al. Among authors: lam y. Bioorg Med Chem. 2010 Sep 15;18(18):6657-65. doi: 10.1016/j.bmc.2010.07.068. Epub 2010 Aug 4. Bioorg Med Chem. 2010. PMID: 20797869

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