Lin28 is induced in primed embryonic stem cells and regulates let-7-independent events.
Parisi S, Passaro F, Russo L, Musto A, Navarra A, Romano S, Petrosino G, Russo T.
Parisi S, et al. Among authors: passaro f.
FASEB J. 2017 Mar;31(3):1046-1058. doi: 10.1096/fj.201600848R. Epub 2016 Dec 5.
FASEB J. 2017.
PMID: 27920151
In summary, we demonstrated that during ESC differentiation, Lin28 transient induction is dependent on Otx2 and Hmga2 and prevents an inappropriate excessive rise of Hmga2 levels.-Parisi, S., Passaro, F., Russo, L., Musto, A., Navarra, A., Romano, S., Petrosino, G., …
In summary, we demonstrated that during ESC differentiation, Lin28 transient induction is dependent on Otx2 and Hmga2 and prevents an inappr …