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HSD3B1 genotype identifies glucocorticoid responsiveness in severe asthma.
Zein J, Gaston B, Bazeley P, DeBoer MD, Igo RP Jr, Bleecker ER, Meyers D, Comhair S, Marozkina NV, Cotton C, Patel M, Alyamani M, Xu W, Busse WW, Calhoun WJ, Ortega V, Hawkins GA, Castro M, Chung KF, Fahy JV, Fitzpatrick AM, Israel E, Jarjour NN, Levy B, Mauger DT, Moore WC, Noel P, Peters SP, Teague WG, Wenzel SE, Erzurum SC, Sharifi N. Zein J, et al. Among authors: alyamani m. Proc Natl Acad Sci U S A. 2020 Jan 28;117(4):2187-2193. doi: 10.1073/pnas.1918819117. Epub 2020 Jan 13. Proc Natl Acad Sci U S A. 2020. PMID: 31932420 Free PMC article. Clinical Trial.
Development and validation of a novel LC-MS/MS method for simultaneous determination of abiraterone and its seven steroidal metabolites in human serum: Innovation in separation of diastereoisomers without use of a chiral column.
Alyamani M, Li Z, Upadhyay SK, Anderson DJ, Auchus RJ, Sharifi N. Alyamani M, et al. J Steroid Biochem Mol Biol. 2017 Sep;172:231-239. doi: 10.1016/j.jsbmb.2016.04.002. Epub 2016 Apr 7. J Steroid Biochem Mol Biol. 2017. PMID: 27063554 Free PMC article.
HSD3B1(1245A>C) variant regulates dueling abiraterone metabolite effects in prostate cancer.
Alyamani M, Emamekhoo H, Park S, Taylor J, Almassi N, Upadhyay S, Tyler A, Berk MP, Hu B, Hwang TH, Figg WD, Peer CJ, Chien C, Koshkin VS, Mendiratta P, Grivas P, Rini B, Garcia J, Auchus RJ, Sharifi N. Alyamani M, et al. J Clin Invest. 2018 Aug 1;128(8):3333-3340. doi: 10.1172/JCI98319. Epub 2018 Jun 25. J Clin Invest. 2018. PMID: 29939161 Free PMC article.
Rapid and structure-specific cellular uptake of selected steroids.
McManus JM, Bohn K, Alyamani M, Chung YM, Klein EA, Sharifi N. McManus JM, et al. Among authors: alyamani m. PLoS One. 2019 Oct 17;14(10):e0224081. doi: 10.1371/journal.pone.0224081. eCollection 2019. PLoS One. 2019. PMID: 31622417 Free PMC article.
72 results