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The Wnt antagonist DICKKOPF-1 gene is induced by 1alpha,25-dihydroxyvitamin D3 associated to the differentiation of human colon cancer cells.
Aguilera O, Peña C, García JM, Larriba MJ, Ordóñez-Morán P, Navarro D, Barbáchano A, López de Silanes I, Ballestar E, Fraga MF, Esteller M, Gamallo C, Bonilla F, González-Sancho JM, Muñoz A. Aguilera O, et al. Among authors: pena c. Carcinogenesis. 2007 Sep;28(9):1877-84. doi: 10.1093/carcin/bgm094. Epub 2007 Apr 21. Carcinogenesis. 2007. PMID: 17449905
DICKKOPF-4 is induced by TCF/beta-catenin and upregulated in human colon cancer, promotes tumour cell invasion and angiogenesis and is repressed by 1alpha,25-dihydroxyvitamin D3.
Pendás-Franco N, García JM, Peña C, Valle N, Pálmer HG, Heinäniemi M, Carlberg C, Jiménez B, Bonilla F, Muñoz A, González-Sancho JM. Pendás-Franco N, et al. Among authors: pena c. Oncogene. 2008 Jul 24;27(32):4467-77. doi: 10.1038/onc.2008.88. Epub 2008 Apr 14. Oncogene. 2008. PMID: 18408752
1,404 results