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Aberrant Epidermal Growth Factor Receptor RNA Splice Products Are Among the Most Frequent Somatic Alterations in Clear Cell Renal Cell Carcinoma and Are Associated with a Poor Response to Immunotherapy.
Zaman S, Hajiran A, Coba GA, Robinson T, Madanayake TW, Segarra DT, Chobrutskiy BI, Boyle TA, Zhou JM, Kim Y, Mulé JJ, Teer JK, Manley BJ. Zaman S, et al. Among authors: mule jj. Eur Urol Focus. 2021 Mar;7(2):373-380. doi: 10.1016/j.euf.2019.12.001. Epub 2019 Dec 31. Eur Urol Focus. 2021. PMID: 31901438 Free PMC article.
Inactivation of RASA1 promotes melanoma tumorigenesis via R-Ras activation.
Sung H, Kanchi KL, Wang X, Hill KS, Messina JL, Lee JH, Kim Y, Dees ND, Ding L, Teer JK, Yang S, Sarnaik AA, Sondak VK, Mulé JJ, Wilson RK, Weber JS, Kim M. Sung H, et al. Among authors: mule jj. Oncotarget. 2016 Apr 26;7(17):23885-96. doi: 10.18632/oncotarget.8127. Oncotarget. 2016. PMID: 26993606 Free PMC article.
Reconnaissance of tumor immune microenvironment spatial heterogeneity in metastatic renal cell carcinoma and correlation with immunotherapy response.
Hajiran A, Chakiryan N, Aydin AM, Zemp L, Nguyen J, Laborde JM, Chahoud J, Spiess PE, Zaman S, Falasiri S, Fournier M, Teer JK, Dhillon J, McCarthy S, Moran-Segura C, Katende EN, Sexton WJ, Koomen JM, Mulé J, Kim Y, Manley B. Hajiran A, et al. Clin Exp Immunol. 2021 Apr;204(1):96-106. doi: 10.1111/cei.13567. Epub 2021 Feb 9. Clin Exp Immunol. 2021. PMID: 33346915 Free PMC article.
Spatial clustering of CD68+ tumor associated macrophages with tumor cells is associated with worse overall survival in metastatic clear cell renal cell carcinoma.
Chakiryan NH, Kimmel GJ, Kim Y, Hajiran A, Aydin AM, Zemp L, Katende E, Nguyen J, Lopez-Blanco N, Chahoud J, Spiess PE, Fournier M, Dhillon J, Wang L, Moran-Segura C, El-Kenawi A, Mulé J, Altrock PM, Manley BJ. Chakiryan NH, et al. PLoS One. 2021 Apr 21;16(4):e0245415. doi: 10.1371/journal.pone.0245415. eCollection 2021. PLoS One. 2021. PMID: 33882057 Free PMC article.
Correlating Immune Cell Infiltration Patterns with Recurrent Somatic Mutations in Advanced Clear Cell Renal Cell Carcinoma.
Chakiryan NH, Hajiran A, Kim Y, Aydin AM, Zemp L, Katende E, Nguyen J, Fan W, Cheng CH, Lopez-Blanco N, Chahoud J, Spiess PE, Fournier M, Dhillon J, Wang L, Moran-Segura C, Mulé J, Du D, Yoder SJ, Berglund A, Teer JK, Manley BJ. Chakiryan NH, et al. Eur Urol Focus. 2022 May;8(3):784-793. doi: 10.1016/j.euf.2021.04.014. Epub 2021 May 11. Eur Urol Focus. 2022. PMID: 33994165 Free PMC article.
The 12-CK Score: Global Measurement of Tertiary Lymphoid Structures.
Li R, Berglund A, Zemp L, Dhillon J, Putney R, Kim Y, Jain RK, Grass GD, Conejo-Garcia J, Mulé JJ. Li R, et al. Among authors: mule jj. Front Immunol. 2021 Jun 29;12:694079. doi: 10.3389/fimmu.2021.694079. eCollection 2021. Front Immunol. 2021. PMID: 34267760 Free PMC article. Review.
Geospatial Cellular Distribution of Cancer-Associated Fibroblasts Significantly Impacts Clinical Outcomes in Metastatic Clear Cell Renal Cell Carcinoma.
Chakiryan NH, Kimmel GJ, Kim Y, Johnson JO, Clark N, Hajiran A, Chang A, Aydin AM, Zemp L, Katende E, Chahoud J, Ferrall-Fairbanks MC, Spiess PE, Francis N, Fournier M, Dhillon J, Park JY, Wang L, Mulé JJ, Altrock PM, Manley BJ. Chakiryan NH, et al. Among authors: mule jj. Cancers (Basel). 2021 Jul 26;13(15):3743. doi: 10.3390/cancers13153743. Cancers (Basel). 2021. PMID: 34359645 Free PMC article.
Quantification of T- and B-cell Immune Receptor Distribution Diversity Characterizes Immune Cell Infiltration and Lymphocyte Heterogeneity in Clear Cell Renal Cell Carcinoma.
Ferrall-Fairbanks MC, Chakiryan NH, Chobrutskiy BI, Kim Y, Teer JK, Berglund A, Mulé JJ, Fournier M, Siegel EM, Dhillon J, Falasiri SSA, Arturo JF, Katende EN, Blanck G, Manley BJ, Altrock PM. Ferrall-Fairbanks MC, et al. Among authors: mule jj. Cancer Res. 2022 Mar 1;82(5):929-942. doi: 10.1158/0008-5472.CAN-21-1747. Cancer Res. 2022. PMID: 35031572 Free PMC article.
The Radiosensitivity Index Gene Signature Identifies Distinct Tumor Immune Microenvironment Characteristics Associated With Susceptibility to Radiation Therapy.
Grass GD, Alfonso JCL, Welsh E, Ahmed KA, Teer JK, Pilon-Thomas S, Harrison LB, Cleveland JL, Mulé JJ, Eschrich SA, Enderling H, Torres-Roca JF. Grass GD, et al. Among authors: mule jj. Int J Radiat Oncol Biol Phys. 2022 Jul 1;113(3):635-647. doi: 10.1016/j.ijrobp.2022.03.006. Epub 2022 Mar 12. Int J Radiat Oncol Biol Phys. 2022. PMID: 35289298 Free PMC article.
181 results