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An in vitro toolbox to accelerate anti-malarial drug discovery and development.
Charman SA, Andreu A, Barker H, Blundell S, Campbell A, Campbell M, Chen G, Chiu FCK, Crighton E, Katneni K, Morizzi J, Patil R, Pham T, Ryan E, Saunders J, Shackleford DM, White KL, Almond L, Dickins M, Smith DA, Moehrle JJ, Burrows JN, Abla N. Charman SA, et al. Among authors: pham t. Malar J. 2020 Jan 2;19(1):1. doi: 10.1186/s12936-019-3075-5. Malar J. 2020. PMID: 31898492 Free PMC article.
Antimalarial Dibenzannulated Medium-Ring Keto Lactams.
Ren R, Wang X, Leas DA, Scheurer C, Hoevel S, Cal M, Chen G, Zhong L, Katneni K, Pham T, Patil R, Sil D, Walters MJ, Schulze TT, Neville AJ, Dong Y, Wittlin S, Kaiser M, Davis PH, Charman SA, Vennerstrom JL. Ren R, et al. Among authors: pham t. ACS Infect Dis. 2023 Oct 13;9(10):1964-1980. doi: 10.1021/acsinfecdis.3c00245. Epub 2023 Sep 11. ACS Infect Dis. 2023. PMID: 37695781 Free PMC article.
Single-Dose Drug Development Candidate for Schistosomiasis.
Leas DA, Keiser J, Charman SA, Shackleford DM, Jones JO, Campbell M, Chen G, Katneni K, Patil R, Hu M, Pham T, Häberli C, Schulze TT, Neville AJ, Wang X, Dong Y, Davis PH, Vennerstrom JL. Leas DA, et al. Among authors: pham t. ACS Infect Dis. 2024 Nov 8;10(11):3963-3972. doi: 10.1021/acsinfecdis.4c00677. Epub 2024 Oct 18. ACS Infect Dis. 2024. PMID: 39423362
Brain-wide cell-type-specific transcriptomic signatures of healthy ageing in mice.
Jin K, Yao Z, van Velthoven CTJ, Kaplan ES, Glattfelder K, Barlow ST, Boyer G, Carey D, Casper T, Chakka AB, Chakrabarty R, Clark M, Departee M, Desierto M, Gary A, Gloe J, Goldy J, Guilford N, Guzman J, Hirschstein D, Lee C, Liang E, Pham T, Reding M, Ronellenfitch K, Ruiz A, Sevigny J, Shapovalova N, Shulga L, Sulc J, Torkelson A, Tung H, Levi B, Sunkin SM, Dee N, Esposito L, Smith KA, Tasic B, Zeng H. Jin K, et al. Among authors: pham t. Nature. 2025 Jan 1. doi: 10.1038/s41586-024-08350-8. Online ahead of print. Nature. 2025. PMID: 39743592
5,177 results