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LINE-1 ORF2p expression is nearly imperceptible in human cancers.
Ardeljan D, Wang X, Oghbaie M, Taylor MS, Husband D, Deshpande V, Steranka JP, Gorbounov M, Yang WR, Sie B, Larman HB, Jiang H, Molloy KR, Altukhov I, Li Z, McKerrow W, Fenyö D, Burns KH, LaCava J. Ardeljan D, et al. Among authors: steranka jp. Mob DNA. 2019 Dec 31;11:1. doi: 10.1186/s13100-019-0191-2. eCollection 2020. Mob DNA. 2019. PMID: 31892958 Free PMC article.
Somatic retrotransposition is infrequent in glioblastomas.
Achanta P, Steranka JP, Tang Z, Rodić N, Sharma R, Yang WR, Ma S, Grivainis M, Huang CRL, Schneider AM, Gallia GL, Riggins GJ, Quinones-Hinojosa A, Fenyö D, Boeke JD, Burns KH. Achanta P, et al. Among authors: steranka jp. Mob DNA. 2016 Nov 11;7:22. doi: 10.1186/s13100-016-0077-5. eCollection 2016. Mob DNA. 2016. PMID: 27843500 Free PMC article.
Cell fitness screens reveal a conflict between LINE-1 retrotransposition and DNA replication.
Ardeljan D, Steranka JP, Liu C, Li Z, Taylor MS, Payer LM, Gorbounov M, Sarnecki JS, Deshpande V, Hruban RH, Boeke JD, Fenyö D, Wu PH, Smogorzewska A, Holland AJ, Burns KH. Ardeljan D, et al. Among authors: steranka jp. Nat Struct Mol Biol. 2020 Feb;27(2):168-178. doi: 10.1038/s41594-020-0372-1. Epub 2020 Feb 10. Nat Struct Mol Biol. 2020. PMID: 32042151 Free PMC article.
Alu insertion variants alter mRNA splicing.
Payer LM, Steranka JP, Ardeljan D, Walker J, Fitzgerald KC, Calabresi PA, Cooper TA, Burns KH. Payer LM, et al. Among authors: steranka jp. Nucleic Acids Res. 2019 Jan 10;47(1):421-431. doi: 10.1093/nar/gky1086. Nucleic Acids Res. 2019. PMID: 30418605 Free PMC article.
16 results