Wright WC - Search Results

1

Discovery and Characterization of the Antimetabolite Action of Thioacetamide-Linked 1,2,3-Triazoles as Disruptors of Cysteine Biosynthesis in Gram-Negative Bacteria.

Wallace MJ, Dharuman S, Fernando DM, Reeve SM, Gee CT, Yao J, Griffith EC, Phelps GA, Wright WC, Elmore JM, Lee RB, Chen T, Lee RE. Wallace MJ, et al. Among authors: wright wc. ACS Infect Dis. 2020 Mar 13;6(3):467-478. doi: 10.1021/acsinfecdis.9b00406. Epub 2020 Jan 13. ACS Infect Dis. 2020. PMID: 31887254 Free PMC article.

2

Differential Regulation of CYP3A4 and CYP3A5 and its Implication in Drug Discovery.

Lolodi O, Wang YM, Wright WC, Chen T. Lolodi O, et al. Among authors: wright wc. Curr Drug Metab. 2017;18(12):1095-1105. doi: 10.2174/1389200218666170531112038. Curr Drug Metab. 2017. PMID: 28558634 Free PMC article. Review.

3

Transcription factor ZNF148 is a negative regulator of human muscle differentiation.

Bakke J, Wright WC, Zamora AE, Ong SS, Wang YM, Hoyer JD, Brewer CT, Thomas PG, Chen T. Bakke J, et al. Among authors: wright wc. Sci Rep. 2017 Aug 15;7(1):8138. doi: 10.1038/s41598-017-08267-5. Sci Rep. 2017. PMID: 28811660 Free PMC article.

4

CINPA1 binds directly to constitutive androstane receptor and inhibits its activity.

Cherian MT, Chai SC, Wright WC, Singh A, Alexandra Casal M, Zheng J, Wu J, Lee RE, Griffin PR, Chen T. Cherian MT, et al. Among authors: wright wc. Biochem Pharmacol. 2018 Jun;152:211-223. doi: 10.1016/j.bcp.2018.03.029. Epub 2018 Mar 31. Biochem Pharmacol. 2018. PMID: 29608908 Free PMC article.

5

RNA interference screen identifies NAA10 as a regulator of PXR transcription.

Oladimeji PO, Wright WC, Wu J, Chen T. Oladimeji PO, et al. Among authors: wright wc. Biochem Pharmacol. 2019 Feb;160:92-109. doi: 10.1016/j.bcp.2018.12.012. Epub 2018 Dec 16. Biochem Pharmacol. 2019. PMID: 30566892 Free PMC article.

6

Genome-wide CRISPR screen reveals PSMA6 to be an essential gene in pancreatic cancer cells.

Bakke J, Wright WC, Zamora AE, Oladimeji P, Crawford JC, Brewer CT, Autry RJ, Evans WE, Thomas PG, Chen T. Bakke J, et al. Among authors: wright wc. BMC Cancer. 2019 Mar 21;19(1):253. doi: 10.1186/s12885-019-5455-1. BMC Cancer. 2019. PMID: 30898113 Free PMC article.

7

Strategies for developing pregnane X receptor antagonists: Implications from metabolism to cancer.

Chai SC, Wright WC, Chen T. Chai SC, et al. Among authors: wright wc. Med Res Rev. 2020 May;40(3):1061-1083. doi: 10.1002/med.21648. Epub 2019 Nov 28. Med Res Rev. 2020. PMID: 31782213 Free PMC article. Review.

8

Clobetasol Propionate Is a Heme-Mediated Selective Inhibitor of Human Cytochrome P450 3A5.

Wright WC, Chenge J, Wang J, Girvan HM, Yang L, Chai SC, Huber AD, Wu J, Oladimeji PO, Munro AW, Chen T. Wright WC, et al. J Med Chem. 2020 Feb 13;63(3):1415-1433. doi: 10.1021/acs.jmedchem.9b02067. Epub 2020 Jan 22. J Med Chem. 2020. PMID: 31965799 Free PMC article.

9

KANSL2 and MBNL3 are regulators of pancreatic ductal adenocarcinoma invasion.

Oladimeji PO, Bakke J, Wright WC, Chen T. Oladimeji PO, et al. Among authors: wright wc. Sci Rep. 2020 Jan 30;10(1):1485. doi: 10.1038/s41598-020-58448-y. Sci Rep. 2020. PMID: 32001790 Free PMC article.

10

Mutation of a single amino acid of pregnane X receptor switches an antagonist to agonist by altering AF-2 helix positioning.

Huber AD, Wright WC, Lin W, Majumder K, Low JA, Wu J, Buchman CD, Pintel DJ, Chen T. Huber AD, et al. Among authors: wright wc. Cell Mol Life Sci. 2021 Jan;78(1):317-335. doi: 10.1007/s00018-020-03505-y. Epub 2020 Mar 30. Cell Mol Life Sci. 2021. PMID: 32232515 Free PMC article.

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