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PPARγ Agonist Pioglitazone in Combination With Cisplatinum Arrests a Chemotherapy-resistant Osteosarcoma PDOX Model.
Higuchi T, Yamamoto J, Sugisawa N, Tashiro Y, Nishino H, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM. Higuchi T, et al. Among authors: kimura h. Cancer Genomics Proteomics. 2020 Jan-Feb;17(1):35-40. doi: 10.21873/cgp.20165. Cancer Genomics Proteomics. 2020. PMID: 31882549 Free PMC article.
Temozolomide regresses a doxorubicin-resistant undifferentiated spindle-cell sarcoma patient-derived orthotopic xenograft (PDOX): precision-oncology nude-mouse model matching the patient with effective therapy.
Igarashi K, Kawaguchi K, Kiyuna T, Miyake K, Miyake M, Li Y, Nelson SD, Dry SM, Singh AS, Elliott IA, Russell TA, Eckardt MA, Yamamoto N, Hayashi K, Kimura H, Miwa S, Tsuchiya H, Eilber FC, Hoffman RM. Igarashi K, et al. Among authors: kimura h. J Cell Biochem. 2018 Aug;119(8):6598-6603. doi: 10.1002/jcb.26792. Epub 2018 May 8. J Cell Biochem. 2018. PMID: 29737543 Clinical Trial.
Oral Recombinant Methioninase Combined with Caffeine and Doxorubicin Induced Regression of a Doxorubicin-resistant Synovial Sarcoma in a PDOX Mouse Model.
Higuchi T, Kawaguchi K, Miyake K, Han Q, Tan Y, Oshiro H, Sugisawa N, Zhang Z, Razmjooei S, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Chawla SP, Singh AS, Eilber FC, Singh SR, Tsuchiya H, Hoffman RM. Higuchi T, et al. Among authors: kimura h. Anticancer Res. 2018 Oct;38(10):5639-5644. doi: 10.21873/anticanres.12899. Anticancer Res. 2018. PMID: 30275182
Metabolic targeting with recombinant methioninase combined with palbociclib regresses a doxorubicin-resistant dedifferentiated liposarcoma.
Igarashi K, Kawaguchi K, Kiyuna T, Miyake K, Miyaki M, Yamamoto N, Hayashi K, Kimura H, Miwa S, Higuchi T, Singh AS, Chmielowski B, Nelson SD, Russell TA, Eckardt MA, Dry SM, Li Y, Singh SR, Chawla SP, Eilber FC, Tsuchiya H, Hoffman RM. Igarashi K, et al. Among authors: kimura h. Biochem Biophys Res Commun. 2018 Dec 2;506(4):912-917. doi: 10.1016/j.bbrc.2018.10.119. Epub 2018 Nov 2. Biochem Biophys Res Commun. 2018. PMID: 30392912
The combination of gemcitabine and nab-paclitaxel as a novel effective treatment strategy for undifferentiated soft-tissue sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model.
Higuchi T, Kawaguchi K, Miyake K, Oshiro H, Zhang Z, Razmjooei S, Wangsiricharoen S, Igarashi K, Yamamoto N, Hayashi K, Kimura H, Miwa S, Nelson SD, Dry SM, Li Y, Chawla SP, Eilber FC, Singh SR, Tsuchiya H, Hoffman RM. Higuchi T, et al. Among authors: kimura h. Biomed Pharmacother. 2019 Mar;111:835-840. doi: 10.1016/j.biopha.2018.12.110. Epub 2019 Jan 4. Biomed Pharmacother. 2019. PMID: 30616082 Free article.
Olaratumab combined with doxorubicin and ifosfamide overcomes individual doxorubicin and olaratumab resistance of an undifferentiated soft-tissue sarcoma in a PDOX mouse model.
Higuchi T, Miyake K, Sugisawa N, Oshiro H, Zhang Z, Razmjooei S, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM. Higuchi T, et al. Among authors: kimura h. Cancer Lett. 2019 Jun 1;451:122-127. doi: 10.1016/j.canlet.2019.03.003. Epub 2019 Mar 10. Cancer Lett. 2019. PMID: 30867142
The combination of olaratumab with gemcitabine and docetaxel arrests a chemotherapy-resistant undifferentiated soft-tissue sarcoma in a patient-derived orthotopic xenograft mouse model.
Higuchi T, Miyake K, Sugisawa N, Oshiro H, Zhang Z, Razmjooei S, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM. Higuchi T, et al. Among authors: kimura h. Cancer Chemother Pharmacol. 2019 Jun;83(6):1075-1082. doi: 10.1007/s00280-019-03824-3. Epub 2019 Mar 30. Cancer Chemother Pharmacol. 2019. PMID: 30929053
Trabectedin and irinotecan combination regresses a cisplatinum-resistant osteosarcoma in a patient-derived orthotopic xenograft nude-mouse model.
Higuchi T, Miyake K, Oshiro H, Sugisawa N, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Chawla SP, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM. Higuchi T, et al. Among authors: kimura h. Biochem Biophys Res Commun. 2019 May 28;513(2):326-331. doi: 10.1016/j.bbrc.2019.03.191. Epub 2019 Apr 5. Biochem Biophys Res Commun. 2019. PMID: 30955860
The Combination of Olaratumab with Doxorubicin and Cisplatinum Regresses a Chemotherapy-Resistant Osteosarcoma in a Patient-Derived Orthotopic Xenograft Mouse Model.
Higuchi T, Sugisawa N, Miyake K, Oshiro H, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM. Higuchi T, et al. Among authors: kimura h. Transl Oncol. 2019 Sep;12(9):1257-1263. doi: 10.1016/j.tranon.2019.06.002. Epub 2019 Jul 9. Transl Oncol. 2019. PMID: 31299622 Free PMC article.
5,920 results