Heuts BMH - Search Results

1

The acute myeloid leukemia associated AML1-ETO fusion protein alters the transcriptome and cellular progression in a single-oncogene expressing in vitro induced pluripotent stem cell based granulocyte differentiation model.

Tijchon E, Yi G, Mandoli A, Smits JGA, Ferrari F, Heuts BMH, Wijnen F, Kim B, Janssen-Megens EM, Schuringa JJ, Martens JHA. Tijchon E, et al. Among authors: heuts bmh. PLoS One. 2019 Dec 23;14(12):e0226435. doi: 10.1371/journal.pone.0226435. eCollection 2019. PLoS One. 2019. PMID: 31869378 Free PMC article.

2

Identification of transcription factors dictating blood cell development using a bidirectional transcription network-based computational framework.

Heuts BMH, Arza-Apalategi S, Frölich S, Bergevoet SM, van den Oever SN, van Heeringen SJ, van der Reijden BA, Martens JHA. Heuts BMH, et al. Sci Rep. 2022 Nov 4;12(1):18656. doi: 10.1038/s41598-022-21148-w. Sci Rep. 2022. PMID: 36333382 Free PMC article.

3

High expression of an intragenic long noncoding RNA misinterpreted as high FTO oncogene expression in NPM1 mutant acute myeloid leukemia.

Arza-Apalategi S, Heuts BMH, Dooijes MTM, Gilissen D, van der Heijden AJP, Jansen JH, Martens JHA, van der Reijden BA. Arza-Apalategi S, et al. Among authors: heuts bmh. Leukemia. 2023 Apr;37(4):901-904. doi: 10.1038/s41375-023-01844-w. Epub 2023 Feb 18. Leukemia. 2023. PMID: 36807648 No abstract available.

4

Inducible MLL-AF9 Expression Drives an AML Program during Human Pluripotent Stem Cell-Derived Hematopoietic Differentiation.

Heuts BMH, Arza-Apalategi S, Alkema SG, Tijchon E, Jussen L, Bergevoet SM, van der Reijden BA, Martens JHA. Heuts BMH, et al. Cells. 2023 Apr 20;12(8):1195. doi: 10.3390/cells12081195. Cells. 2023. PMID: 37190104 Free PMC article.

5

Saponin-based adjuvants enhance antigen cross-presentation in human CD11c⁺ CD1c⁺ CD5^- CD163⁺ conventional type 2 dendritic cells.

Ho NI, Huis In 't Veld LGM, van Eck van der Sluijs J, Heuts BMH, Looman MWG, Kers-Rebel ED, van den Dries K, Dolstra H, Martens JHA, Hobo W, Adema GJ. Ho NI, et al. Among authors: heuts bmh. J Immunother Cancer. 2023 Aug;11(8):e007082. doi: 10.1136/jitc-2023-007082. J Immunother Cancer. 2023. PMID: 37612044 Free PMC article.

6

Understanding blood development and leukemia using sequencing-based technologies and human cell systems.

Heuts BMH, Martens JHA. Heuts BMH, et al. Front Mol Biosci. 2023 Oct 10;10:1266697. doi: 10.3389/fmolb.2023.1266697. eCollection 2023. Front Mol Biosci. 2023. PMID: 37886034 Free PMC article. Review.

7

scANANSE gene regulatory network and motif analysis of single-cell clusters.

Smits JGA, Arts JA, Frölich S, Snabel RR, Heuts BMH, Martens JHA, van Heeringen SJ, Zhou H. Smits JGA, et al. Among authors: heuts bmh. F1000Res. 2023 Mar 6;12:243. doi: 10.12688/f1000research.130530.1. eCollection 2023. F1000Res. 2023. PMID: 38116584 Free PMC article.

8

HMX3 is a critical vulnerability in MECOM-negative KMT2A::MLLT3 acute myelomonocytic leukemia.

Arza-Apalategi S, Heuts BMH, Bergevoet SM, Meering R, Gilissen D, Jansen PWTC, Krippner-Heidenreich A, Valk PJM, Vermeulen M, Heidenreich O, Haferlach T, Jansen JH, Martens JHA, van der Reijden BA. Arza-Apalategi S, et al. Among authors: heuts bmh. Leukemia. 2024 Dec 4. doi: 10.1038/s41375-024-02485-3. Online ahead of print. Leukemia. 2024. PMID: 39633068

9

Combined quantification of intracellular (phospho-)proteins and transcriptomics from fixed single cells.

Gerlach JP, van Buggenum JAG, Tanis SEJ, Hogeweg M, Heuts BMH, Muraro MJ, Elze L, Rivello F, Rakszewska A, van Oudenaarden A, Huck WTS, Stunnenberg HG, Mulder KW. Gerlach JP, et al. Among authors: heuts bmh. Sci Rep. 2019 Feb 6;9(1):1469. doi: 10.1038/s41598-018-37977-7. Sci Rep. 2019. PMID: 30728416 Free PMC article.

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