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Undetectable gadolinium brain retention in individuals with an age-dependent blood-brain barrier breakdown in the hippocampus and mild cognitive impairment.
Montagne A, Huuskonen MT, Rajagopal G, Sweeney MD, Nation DA, Sepehrband F, D'Orazio LM, Harrington MG, Chui HC, Law M, Toga AW, Zlokovic BV. Montagne A, et al. Among authors: huuskonen mt. Alzheimers Dement. 2019 Dec;15(12):1568-1575. doi: 10.1016/j.jalz.2019.07.012. Alzheimers Dement. 2019. PMID: 31862169 Free PMC article.
Endothelial LRP1 protects against neurodegeneration by blocking cyclophilin A.
Nikolakopoulou AM, Wang Y, Ma Q, Sagare AP, Montagne A, Huuskonen MT, Rege SV, Kisler K, Dai Z, Körbelin J, Herz J, Zhao Z, Zlokovic BV. Nikolakopoulou AM, et al. Among authors: huuskonen mt. J Exp Med. 2021 Apr 5;218(4):e20202207. doi: 10.1084/jem.20202207. J Exp Med. 2021. PMID: 33533918 Free PMC article.
Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss.
Nikolakopoulou AM, Montagne A, Kisler K, Dai Z, Wang Y, Huuskonen MT, Sagare AP, Lazic D, Sweeney MD, Kong P, Wang M, Owens NC, Lawson EJ, Xie X, Zhao Z, Zlokovic BV. Nikolakopoulou AM, et al. Among authors: huuskonen mt. Nat Neurosci. 2019 Jul;22(7):1089-1098. doi: 10.1038/s41593-019-0434-z. Epub 2019 Jun 24. Nat Neurosci. 2019. PMID: 31235908 Free PMC article.
A "multi-omics" analysis of blood-brain barrier and synaptic dysfunction in APOE4 mice.
Barisano G, Kisler K, Wilkinson B, Nikolakopoulou AM, Sagare AP, Wang Y, Gilliam W, Huuskonen MT, Hung ST, Ichida JK, Gao F, Coba MP, Zlokovic BV. Barisano G, et al. Among authors: huuskonen mt. J Exp Med. 2022 Nov 7;219(11):e20221137. doi: 10.1084/jem.20221137. Epub 2022 Aug 30. J Exp Med. 2022. PMID: 36040482 Free PMC article.
A Review of Translational Magnetic Resonance Imaging in Human and Rodent Experimental Models of Small Vessel Disease.
Stringer MS, Lee H, Huuskonen MT, MacIntosh BJ, Brown R, Montagne A, Atwi S, Ramirez J, Jansen MA, Marshall I, Black SE, Zlokovic BV, Benveniste H, Wardlaw JM. Stringer MS, et al. Among authors: huuskonen mt. Transl Stroke Res. 2021 Feb;12(1):15-30. doi: 10.1007/s12975-020-00843-8. Epub 2020 Sep 16. Transl Stroke Res. 2021. PMID: 32936435 Free PMC article.
29 results