Offermanns S - Search Results

1

Helix 8 is the essential structural motif of mechanosensitive GPCRs.

Erdogmus S, Storch U, Danner L, Becker J, Winter M, Ziegler N, Wirth A, Offermanns S, Hoffmann C, Gudermann T, Mederos Y Schnitzler M. Erdogmus S, et al. Among authors: offermanns s. Nat Commun. 2019 Dec 19;10(1):5784. doi: 10.1038/s41467-019-13722-0. Nat Commun. 2019. PMID: 31857598 Free PMC article.

2

G13 is an essential mediator of platelet activation in hemostasis and thrombosis.

Moers A, Nieswandt B, Massberg S, Wettschureck N, Grüner S, Konrad I, Schulte V, Aktas B, Gratacap MP, Simon MI, Gawaz M, Offermanns S. Moers A, et al. Among authors: offermanns s. Nat Med. 2003 Nov;9(11):1418-22. doi: 10.1038/nm943. Epub 2003 Oct 5. Nat Med. 2003. PMID: 14528298

3

G12-G13-LARG-mediated signaling in vascular smooth muscle is required for salt-induced hypertension.

Wirth A, Benyó Z, Lukasova M, Leutgeb B, Wettschureck N, Gorbey S, Orsy P, Horváth B, Maser-Gluth C, Greiner E, Lemmer B, Schütz G, Gutkind JS, Offermanns S. Wirth A, et al. Among authors: offermanns s. Nat Med. 2008 Jan;14(1):64-8. doi: 10.1038/nm1666. Epub 2007 Dec 16. Nat Med. 2008. PMID: 18084302

4

Anaphylactic shock depends on endothelial Gq/G11.

Korhonen H, Fisslthaler B, Moers A, Wirth A, Habermehl D, Wieland T, Schütz G, Wettschureck N, Fleming I, Offermanns S. Korhonen H, et al. Among authors: offermanns s. J Exp Med. 2009 Feb 16;206(2):411-20. doi: 10.1084/jem.20082150. Epub 2009 Jan 26. J Exp Med. 2009. PMID: 19171764 Free PMC article.

5

Smooth muscle-specific deletion of nitric oxide-sensitive guanylyl cyclase is sufficient to induce hypertension in mice.

Groneberg D, König P, Wirth A, Offermanns S, Koesling D, Friebe A. Groneberg D, et al. Among authors: offermanns s. Circulation. 2010 Jan 26;121(3):401-9. doi: 10.1161/CIRCULATIONAHA.109.890962. Epub 2010 Jan 11. Circulation. 2010. PMID: 20065162

6

Nicotinic acid- and monomethyl fumarate-induced flushing involves GPR109A expressed by keratinocytes and COX-2-dependent prostanoid formation in mice.

Hanson J, Gille A, Zwykiel S, Lukasova M, Clausen BE, Ahmed K, Tunaru S, Wirth A, Offermanns S. Hanson J, et al. Among authors: offermanns s. J Clin Invest. 2010 Aug;120(8):2910-9. doi: 10.1172/JCI42273. Epub 2010 Jul 26. J Clin Invest. 2010. PMID: 20664170 Free PMC article.

7

Activation of TRPC6 channels is essential for lung ischaemia-reperfusion induced oedema in mice.

Weissmann N, Sydykov A, Kalwa H, Storch U, Fuchs B, Mederos y Schnitzler M, Brandes RP, Grimminger F, Meissner M, Freichel M, Offermanns S, Veit F, Pak O, Krause KH, Schermuly RT, Brewer AC, Schmidt HH, Seeger W, Shah AM, Gudermann T, Ghofrani HA, Dietrich A. Weissmann N, et al. Among authors: offermanns s. Nat Commun. 2012 Jan 31;3:649. doi: 10.1038/ncomms1660. Nat Commun. 2012. PMID: 22337127 Free PMC article.

8

G(13)-mediated signaling pathway is required for pressure overload-induced cardiac remodeling and heart failure.

Takefuji M, Wirth A, Lukasova M, Takefuji S, Boettger T, Braun T, Althoff T, Offermanns S, Wettschureck N. Takefuji M, et al. Among authors: offermanns s. Circulation. 2012 Oct 16;126(16):1972-82. doi: 10.1161/CIRCULATIONAHA.112.109256. Epub 2012 Sep 12. Circulation. 2012. PMID: 22972902

9

Procontractile G protein-mediated signaling pathways antagonistically regulate smooth muscle differentiation in vascular remodeling.

Althoff TF, Albarrán Juárez J, Troidl K, Tang C, Wang S, Wirth A, Takefuji M, Wettschureck N, Offermanns S. Althoff TF, et al. Among authors: offermanns s. J Exp Med. 2012 Nov 19;209(12):2277-90. doi: 10.1084/jem.20120350. Epub 2012 Nov 5. J Exp Med. 2012. PMID: 23129751 Free PMC article.

10

The β-hydroxybutyrate receptor HCA2 activates a neuroprotective subset of macrophages.

Rahman M, Muhammad S, Khan MA, Chen H, Ridder DA, Müller-Fielitz H, Pokorná B, Vollbrandt T, Stölting I, Nadrowitz R, Okun JG, Offermanns S, Schwaninger M. Rahman M, et al. Among authors: offermanns s. Nat Commun. 2014 May 21;5:3944. doi: 10.1038/ncomms4944. Nat Commun. 2014. PMID: 24845831 Free article.

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