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145 results

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Deubiquitinase Activity Profiling Identifies UCHL1 as a Candidate Oncoprotein That Promotes TGFβ-Induced Breast Cancer Metastasis.
Liu S, González-Prieto R, Zhang M, Geurink PP, Kooij R, Iyengar PV, van Dinther M, Bos E, Zhang X, Le Dévédec SE, van de Water B, Koning RI, Zhu HJ, Mesker WE, Vertegaal ACO, Ovaa H, Zhang L, Martens JWM, Ten Dijke P. Liu S, et al. Among authors: mesker we. Clin Cancer Res. 2020 Mar 15;26(6):1460-1473. doi: 10.1158/1078-0432.CCR-19-1373. Epub 2019 Dec 19. Clin Cancer Res. 2020. PMID: 31857432 Free PMC article.
The prognostic role of TGF-β signaling pathway in breast cancer patients.
de Kruijf EM, Dekker TJA, Hawinkels LJAC, Putter H, Smit VTHBM, Kroep JR, Kuppen PJK, van de Velde CJH, Ten Dijke P, Tollenaar RAEM, Mesker WE. de Kruijf EM, et al. Among authors: mesker we. Ann Oncol. 2013 Feb;24(2):384-390. doi: 10.1093/annonc/mds333. Epub 2012 Sep 28. Ann Oncol. 2013. PMID: 23022998 Free article.
Prognostic significance of the tumor-stroma ratio: validation study in node-negative premenopausal breast cancer patients from the EORTC perioperative chemotherapy (POP) trial (10854).
Dekker TJ, van de Velde CJ, van Pelt GW, Kroep JR, Julien JP, Smit VT, Tollenaar RA, Mesker WE. Dekker TJ, et al. Among authors: mesker we. Breast Cancer Res Treat. 2013 Jun;139(2):371-9. doi: 10.1007/s10549-013-2571-5. Epub 2013 May 25. Breast Cancer Res Treat. 2013. PMID: 23709090
TRAF4 promotes TGF-β receptor signaling and drives breast cancer metastasis.
Zhang L, Zhou F, García de Vinuesa A, de Kruijf EM, Mesker WE, Hui L, Drabsch Y, Li Y, Bauer A, Rousseau A, Sheppard KA, Mickanin C, Kuppen PJ, Lu CX, Ten Dijke P. Zhang L, et al. Among authors: mesker we. Mol Cell. 2013 Sep 12;51(5):559-72. doi: 10.1016/j.molcel.2013.07.014. Epub 2013 Aug 22. Mol Cell. 2013. PMID: 23973329 Free article.
The BMP pathway either enhances or inhibits the Wnt pathway depending on the SMAD4 and p53 status in CRC.
Voorneveld PW, Kodach LL, Jacobs RJ, van Noesel CJ, Peppelenbosch MP, Korkmaz KS, Molendijk I, Dekker E, Morreau H, van Pelt GW, Tollenaar RA, Mesker W, Hawinkels LJ, Paauwe M, Verspaget HW, Geraets DT, Hommes DW, Offerhaus GJ, van den Brink GR, Ten Dijke P, Hardwick JC. Voorneveld PW, et al. Br J Cancer. 2015 Jan 6;112(1):122-30. doi: 10.1038/bjc.2014.560. Epub 2014 Nov 13. Br J Cancer. 2015. PMID: 25393365 Free PMC article.
Disorganised stroma determined on pre-treatment breast cancer biopsies is associated with poor response to neoadjuvant chemotherapy: Results from the NEOZOTAC trial.
Dekker TJ, Charehbili A, Smit VT, ten Dijke P, Kranenbarg EM, van de Velde CJ, Nortier JW, Tollenaar RA, Mesker WE, Kroep JR. Dekker TJ, et al. Among authors: mesker we. Mol Oncol. 2015 Jun;9(6):1120-8. doi: 10.1016/j.molonc.2015.02.001. Epub 2015 Feb 14. Mol Oncol. 2015. PMID: 25735561 Free PMC article. Clinical Trial.
145 results