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117 results

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Page 1
Human genetics and neuropathology suggest a link between miR-218 and amyotrophic lateral sclerosis pathophysiology.
Reichenstein I, Eitan C, Diaz-Garcia S, Haim G, Magen I, Siany A, Hoye ML, Rivkin N, Olender T, Toth B, Ravid R, Mandelbaum AD, Yanowski E, Liang J, Rymer JK, Levy R, Beck G, Ainbinder E, Farhan SMK, Lennox KA, Bode NM, Behlke MA, Möller T, Saxena S, Moreno CAM, Costaguta G, van Eijk KR, Phatnani H, Al-Chalabi A, Başak AN, van den Berg LH, Hardiman O, Landers JE, Mora JS, Morrison KE, Shaw PJ, Veldink JH, Pfaff SL, Yizhar O, Gross C, Brown RH Jr, Ravits JM, Harms MB, Miller TM, Hornstein E. Reichenstein I, et al. Among authors: pfaff sl. Sci Transl Med. 2019 Dec 18;11(523):eaav5264. doi: 10.1126/scitranslmed.aav5264. Sci Transl Med. 2019. PMID: 31852800 Free PMC article.
Survival of syngeneic and allogeneic iPSC-derived neural precursors after spinal grafting in minipigs.
Strnadel J, Carromeu C, Bardy C, Navarro M, Platoshyn O, Glud AN, Marsala S, Kafka J, Miyanohara A, Kato T Jr, Tadokoro T, Hefferan MP, Kamizato K, Yoshizumi T, Juhas S, Juhasova J, Ho CS, Kheradmand T, Chen P, Bohaciakova D, Hruska-Plochan M, Todd AJ, Driscoll SP, Glenn TD, Pfaff SL, Klima J, Ciacci J, Curtis E, Gage FH, Bui J, Yamada K, Muotri AR, Marsala M. Strnadel J, et al. Among authors: pfaff sl. Sci Transl Med. 2018 May 9;10(440):eaam6651. doi: 10.1126/scitranslmed.aam6651. Sci Transl Med. 2018. PMID: 29743351 Free article.
Spinal subpial delivery of AAV9 enables widespread gene silencing and blocks motoneuron degeneration in ALS.
Bravo-Hernandez M, Tadokoro T, Navarro MR, Platoshyn O, Kobayashi Y, Marsala S, Miyanohara A, Juhas S, Juhasova J, Skalnikova H, Tomori Z, Vanicky I, Studenovska H, Proks V, Chen P, Govea-Perez N, Ditsworth D, Ciacci JD, Gao S, Zhu W, Ahrens ET, Driscoll SP, Glenn TD, McAlonis-Downes M, Da Cruz S, Pfaff SL, Kaspar BK, Cleveland DW, Marsala M. Bravo-Hernandez M, et al. Among authors: pfaff sl. Nat Med. 2020 Jan;26(1):118-130. doi: 10.1038/s41591-019-0674-1. Epub 2019 Dec 23. Nat Med. 2020. PMID: 31873312 Free PMC article.
Mitf is a Schwann cell sensor of axonal integrity that drives nerve repair.
Daboussi L, Costaguta G, Gullo M, Jasinski N, Pessino V, O'Leary B, Lettieri K, Driscoll S, Pfaff SL. Daboussi L, et al. Among authors: pfaff sl. Cell Rep. 2023 Nov 28;42(11):113282. doi: 10.1016/j.celrep.2023.113282. Epub 2023 Oct 28. Cell Rep. 2023. PMID: 38007688 Free PMC article.
Motor axon pathfinding.
Bonanomi D, Pfaff SL. Bonanomi D, et al. Among authors: pfaff sl. Cold Spring Harb Perspect Biol. 2010 Mar;2(3):a001735. doi: 10.1101/cshperspect.a001735. Cold Spring Harb Perspect Biol. 2010. PMID: 20300210 Free PMC article. Review.
Loss of motoneuron-specific microRNA-218 causes systemic neuromuscular failure.
Amin ND, Bai G, Klug JR, Bonanomi D, Pankratz MT, Gifford WD, Hinckley CA, Sternfeld MJ, Driscoll SP, Dominguez B, Lee KF, Jin X, Pfaff SL. Amin ND, et al. Among authors: pfaff sl. Science. 2015 Dec 18;350(6267):1525-9. doi: 10.1126/science.aad2509. Science. 2015. PMID: 26680198 Free PMC article.
117 results