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DNA vaccination before conception protects Zika virus-exposed pregnant macaques against prolonged viremia and improves fetal outcomes.
Van Rompay KKA, Keesler RI, Ardeshir A, Watanabe J, Usachenko J, Singapuri A, Cruzen C, Bliss-Moreau E, Murphy AM, Yee JL, Webster H, Dennis M, Singh T, Heimsath H, Lemos D, Stuart J, Morabito KM, Foreman BM, Burgomaster KE, Noe AT, Dowd KA, Ball E, Woolard K, Presicce P, Kallapur SG, Permar SR, Foulds KE, Coffey LL, Pierson TC, Graham BS. Van Rompay KKA, et al. Among authors: singapuri a. Sci Transl Med. 2019 Dec 18;11(523):eaay2736. doi: 10.1126/scitranslmed.aay2736. Sci Transl Med. 2019. PMID: 31852797 Free PMC article.
Zika Virus Tissue and Blood Compartmentalization in Acute Infection of Rhesus Macaques.
Coffey LL, Pesavento PA, Keesler RI, Singapuri A, Watanabe J, Watanabe R, Yee J, Bliss-Moreau E, Cruzen C, Christe KL, Reader JR, von Morgenland W, Gibbons AM, Allen AM, Linnen J, Gao K, Delwart E, Simmons G, Stone M, Lanteri M, Bakkour S, Busch M, Morrison J, Van Rompay KK. Coffey LL, et al. Among authors: singapuri a. PLoS One. 2017 Jan 31;12(1):e0171148. doi: 10.1371/journal.pone.0171148. eCollection 2017. PLoS One. 2017. PMID: 28141843 Free PMC article.
Intraamniotic Zika virus inoculation of pregnant rhesus macaques produces fetal neurologic disease.
Coffey LL, Keesler RI, Pesavento PA, Woolard K, Singapuri A, Watanabe J, Cruzen C, Christe KL, Usachenko J, Yee J, Heng VA, Bliss-Moreau E, Reader JR, von Morgenland W, Gibbons AM, Jackson K, Ardeshir A, Heimsath H, Permar S, Senthamaraikannan P, Presicce P, Kallapur SG, Linnen JM, Gao K, Orr R, MacGill T, McClure M, McFarland R, Morrison JH, Van Rompay KKA. Coffey LL, et al. Among authors: singapuri a. Nat Commun. 2018 Jun 20;9(1):2414. doi: 10.1038/s41467-018-04777-6. Nat Commun. 2018. PMID: 29925843 Free PMC article.
A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates.
Keeffe JR, Van Rompay KKA, Olsen PC, Wang Q, Gazumyan A, Azzopardi SA, Schaefer-Babajew D, Lee YE, Stuart JB, Singapuri A, Watanabe J, Usachenko J, Ardeshir A, Saeed M, Agudelo M, Eisenreich T, Bournazos S, Oliveira TY, Rice CM, Coffey LL, MacDonald MR, Bjorkman PJ, Nussenzweig MC, Robbiani DF. Keeffe JR, et al. Among authors: singapuri a. Cell Rep. 2018 Nov 6;25(6):1385-1394.e7. doi: 10.1016/j.celrep.2018.10.031. Cell Rep. 2018. PMID: 30403995 Free PMC article.
Postnatal Zika virus infection of nonhuman primate infants born to mothers infected with homologous Brazilian Zika virus.
Maness NJ, Schouest B, Singapuri A, Dennis M, Gilbert MH, Bohm RP, Schiro F, Aye PP, Baker K, Van Rompay KKA, Lackner AA, Bonaldo MC, Blair RV, Permar SR, Coffey LL, Panganiban AT, Magnani D. Maness NJ, et al. Among authors: singapuri a. Sci Rep. 2019 Sep 5;9(1):12802. doi: 10.1038/s41598-019-49209-7. Sci Rep. 2019. PMID: 31488856 Free PMC article.
A combination of two human monoclonal antibodies limits fetal damage by Zika virus in macaques.
Van Rompay KKA, Coffey LL, Kapoor T, Gazumyan A, Keesler RI, Jurado A, Peace A, Agudelo M, Watanabe J, Usachenko J, Singapuri A, Immareddy R, Ardeshir A, Stuart JB, Bournazos S, Ravetch JV, Balderes PJ, Lorenz IC, Esswein SR, Keeffe JR, Bjorkman PJ, Wang Q, Rice CM, MacDonald MR, Nussenzweig MC, Robbiani DF. Van Rompay KKA, et al. Among authors: singapuri a. Proc Natl Acad Sci U S A. 2020 Apr 7;117(14):7981-7989. doi: 10.1073/pnas.2000414117. Epub 2020 Mar 24. Proc Natl Acad Sci U S A. 2020. PMID: 32209664 Free PMC article.
Two Sides of a Coin: a Zika Virus Mutation Selected in Pregnant Rhesus Macaques Promotes Fetal Infection in Mice but at a Cost of Reduced Fitness in Nonpregnant Macaques and Diminished Transmissibility by Vectors.
Lemos D, Stuart JB, Louie W, Singapuri A, Ramírez AL, Watanabe J, Usachenko J, Keesler RI, Sanchez-San Martin C, Li T, Martyn C, Oliveira G, Saraf S, Grubaugh ND, Andersen KG, Thissen J, Allen J, Borucki M, Tsetsarkin KA, Pletnev AG, Chiu CY, Van Rompay KKA, Coffey LL. Lemos D, et al. Among authors: singapuri a. J Virol. 2020 Nov 23;94(24):e01605-20. doi: 10.1128/JVI.01605-20. Print 2020 Nov 23. J Virol. 2020. PMID: 32999034 Free PMC article.
Evolution of ocular defects in infant macaques following in utero Zika virus infection.
Yiu G, Thomasy SM, Casanova MI, Rusakevich A, Keesler RI, Watanabe J, Usachenko J, Singapuri A, Ball EE, Bliss-Moreau E, Guo W, Webster H, Singh T, Permar S, Ardeshir A, Coffey LL, Van Rompay KK. Yiu G, et al. Among authors: singapuri a. JCI Insight. 2020 Dec 17;5(24):e143947. doi: 10.1172/jci.insight.143947. JCI Insight. 2020. PMID: 33180748 Free PMC article.
95 results