The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation.
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Franklin BS, et al. Among authors: engels g.
Nat Immunol. 2014 Aug;15(8):727-37. doi: 10.1038/ni.2913. Epub 2014 Jun 22.
Nat Immunol. 2014.
PMID: 24952505
Free PMC article.