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Convergence of linkage, gene expression and association data demonstrates the influence of the RAR-related orphan receptor alpha (RORA) gene on neovascular AMD: a systems biology based approach.
Silveira AC, Morrison MA, Ji F, Xu H, Reinecke JB, Adams SM, Arneberg TM, Janssian M, Lee JE, Yuan Y, Schaumberg DA, Kotoula MG, Tsironi EE, Tsiloulis AN, Chatzoulis DZ, Miller JW, Kim IK, Hageman GS, Farrer LA, Haider NB, DeAngelis MM. Silveira AC, et al. Vision Res. 2010 Mar 31;50(7):698-715. doi: 10.1016/j.visres.2009.09.016. Epub 2009 Sep 26. Vision Res. 2010. PMID: 19786043 Free PMC article.
Influence of ROBO1 and RORA on risk of age-related macular degeneration reveals genetically distinct phenotypes in disease pathophysiology.
Jun G, Nicolaou M, Morrison MA, Buros J, Morgan DJ, Radeke MJ, Yonekawa Y, Tsironi EE, Kotoula MG, Zacharaki F, Mollema N, Yuan Y, Miller JW, Haider NB, Hageman GS, Kim IK, Schaumberg DA, Farrer LA, DeAngelis MM. Jun G, et al. PLoS One. 2011;6(10):e25775. doi: 10.1371/journal.pone.0025775. Epub 2011 Oct 6. PLoS One. 2011. PMID: 21998696 Free PMC article.
Systems biology-based analysis implicates a novel role for vitamin D metabolism in the pathogenesis of age-related macular degeneration.
Morrison MA, Silveira AC, Huynh N, Jun G, Smith SE, Zacharaki F, Sato H, Loomis S, Andreoli MT, Adams SM, Radeke MJ, Jelcick AS, Yuan Y, Tsiloulis AN, Chatzoulis DZ, Silvestri G, Kotoula MG, Tsironi EE, Hollis BW, Chen R, Haider NB, Miller JW, Farrer LA, Hageman GS, Kim IK, Schaumberg DA, DeAngelis MM. Morrison MA, et al. Hum Genomics. 2011 Oct;5(6):538-68. doi: 10.1186/1479-7364-5-6-538. Hum Genomics. 2011. PMID: 22155603 Free PMC article.
High throughput mass spectrometry-based mutation profiling of primary uveal melanoma.
Daniels AB, Lee JE, MacConaill LE, Palescandolo E, Van Hummelen P, Adams SM, DeAngelis MM, Hahn WC, Gragoudas ES, Harbour JW, Garraway LA, Kim IK. Daniels AB, et al. Invest Ophthalmol Vis Sci. 2012 Oct 9;53(11):6991-6. doi: 10.1167/iovs.12-10427. Invest Ophthalmol Vis Sci. 2012. PMID: 22977135 Free PMC article.
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