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Monoclonal IgG antibodies generated from joint-derived B cells of RA patients have a strong bias toward citrullinated autoantigen recognition.
Amara K, Steen J, Murray F, Morbach H, Fernandez-Rodriguez BM, Joshua V, Engström M, Snir O, Israelsson L, Catrina AI, Wardemann H, Corti D, Meffre E, Klareskog L, Malmström V. Amara K, et al. Among authors: malmstrom v. J Exp Med. 2013 Mar 11;210(3):445-55. doi: 10.1084/jem.20121486. Epub 2013 Feb 25. J Exp Med. 2013. Retraction in: J Exp Med. 2019 Jan 7;216(1):245. doi: 10.1084/jem.2012148612112018r PMID: 23440041 Free PMC article. Retracted.
Environmental and genetic factors in the development of anticitrullinated protein antibodies (ACPAs) and ACPA-positive rheumatoid arthritis: an epidemiological investigation in twins.
Hensvold AH, Magnusson PK, Joshua V, Hansson M, Israelsson L, Ferreira R, Jakobsson PJ, Holmdahl R, Hammarström L, Malmström V, Askling J, Klareskog L, Catrina AI. Hensvold AH, et al. Among authors: malmstrom v. Ann Rheum Dis. 2015 Feb;74(2):375-80. doi: 10.1136/annrheumdis-2013-203947. Epub 2013 Nov 25. Ann Rheum Dis. 2015. PMID: 24276366
Shared immunological targets in the lungs and joints of patients with rheumatoid arthritis: identification and validation.
Ytterberg AJ, Joshua V, Reynisdottir G, Tarasova NK, Rutishauser D, Ossipova E, Haj Hensvold A, Eklund A, Sköld CM, Grunewald J, Malmström V, Jakobsson PJ, Rönnelid J, Padyukov L, Zubarev RA, Klareskog L, Catrina AI. Ytterberg AJ, et al. Among authors: malmstrom v. Ann Rheum Dis. 2015 Sep;74(9):1772-7. doi: 10.1136/annrheumdis-2013-204912. Epub 2014 May 9. Ann Rheum Dis. 2015. PMID: 24817415
Affinity purified anti-citrullinated protein/peptide antibodies target antigens expressed in the rheumatoid joint.
Ossipova E, Cerqueira CF, Reed E, Kharlamova N, Israelsson L, Holmdahl R, Nandakumar KS, Engström M, Harre U, Schett G, Catrina AI, Malmström V, Sommarin Y, Klareskog L, Jakobsson PJ, Lundberg K. Ossipova E, et al. Among authors: malmstrom v. Arthritis Res Ther. 2014 Aug 12;16(4):R167. doi: 10.1186/ar4683. Arthritis Res Ther. 2014. PMID: 25112157 Free PMC article.
176 results