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Disrupting MLV integrase:BET protein interaction biases integration into quiescent chromatin and delays but does not eliminate tumor activation in a MYC/Runx2 mouse model.
Loyola L, Achuthan V, Gilroy K, Borland G, Kilbey A, Mackay N, Bell M, Hay J, Aiyer S, Fingerman D, Villanueva RA, Cameron E, Kozak CA, Engelman AN, Neil J, Roth MJ. Loyola L, et al. Among authors: hay j. PLoS Pathog. 2019 Dec 9;15(12):e1008154. doi: 10.1371/journal.ppat.1008154. eCollection 2019 Dec. PLoS Pathog. 2019. PMID: 31815961 Free PMC article.
RUNX oncoproteins and miRNA networks.
Neil JC, Hay J, Borland G. Neil JC, et al. Among authors: hay j. Oncotarget. 2017 Sep 7;8(38):62818-62819. doi: 10.18632/oncotarget.20673. eCollection 2017 Sep 8. Oncotarget. 2017. PMID: 28968950 Free PMC article. No abstract available.
IL-27 maintains cytotoxic Ly6C+ γδ T cells that arise from immature precursors.
Wiesheu R, Edwards SC, Hedley A, Hall H, Tosolini M, Fares da Silva MGF, Sumaria N, Castenmiller SM, Wardak L, Optaczy Y, Lynn A, Hill DG, Hayes AJ, Hay J, Kilbey A, Shaw R, Whyte D, Walsh PJ, Michie AM, Graham GJ, Manoharan A, Halsey C, Blyth K, Wolkers MC, Miller C, Pennington DJ, Jones GW, Fournie JJ, Bekiaris V, Coffelt SB. Wiesheu R, et al. Among authors: hay j. EMBO J. 2024 Jul;43(14):2878-2907. doi: 10.1038/s44318-024-00133-1. Epub 2024 May 30. EMBO J. 2024. PMID: 38816652 Free PMC article.
AKT/mTORC2 Inhibition Activates FOXO1 Function in CLL Cells Reducing B-Cell Receptor-Mediated Survival.
Cosimo E, Tarafdar A, Moles MW, Holroyd AK, Malik N, Catherwood MA, Hay J, Dunn KM, Macdonald AM, Guichard SM, O'Rourke D, Leach MT, Sansom OJ, Cosulich SC, McCaig AM, Michie AM. Cosimo E, et al. Among authors: hay j. Clin Cancer Res. 2019 Mar 1;25(5):1574-1587. doi: 10.1158/1078-0432.CCR-18-2036. Epub 2018 Dec 17. Clin Cancer Res. 2019. PMID: 30559170 Free PMC article.
1,776 results