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Functional genomics and gene-environment interaction highlight the complexity of congenital heart disease caused by Notch pathway variants.
Chapman G, Moreau JLM, I P E, Szot JO, Iyer KR, Shi H, Yam MX, O'Reilly VC, Enriquez A, Greasby JA, Alankarage D, Martin EMMA, Hanna BC, Edwards M, Monger S, Blue GM, Winlaw DS, Ritchie HE, Grieve SM, Giannoulatou E, Sparrow DB, Dunwoodie SL. Chapman G, et al. Among authors: moreau jlm. Hum Mol Genet. 2020 Mar 13;29(4):566-579. doi: 10.1093/hmg/ddz270. Hum Mol Genet. 2020. PMID: 31813956 Free PMC article.
Gene-environment interaction impacts on heart development and embryo survival.
Moreau JLM, Kesteven S, Martin EMMA, Lau KS, Yam MX, O'Reilly VC, Del Monte-Nieto G, Baldini A, Feneley MP, Moon AM, Harvey RP, Sparrow DB, Chapman G, Dunwoodie SL. Moreau JLM, et al. Development. 2019 Feb 20;146(4):dev172957. doi: 10.1242/dev.172957. Development. 2019. PMID: 30787001
NAD Deficiency, Congenital Malformations, and Niacin Supplementation.
Shi H, Enriquez A, Rapadas M, Martin EMMA, Wang R, Moreau J, Lim CK, Szot JO, Ip E, Hughes JN, Sugimoto K, Humphreys DT, McInerney-Leo AM, Leo PJ, Maghzal GJ, Halliday J, Smith J, Colley A, Mark PR, Collins F, Sillence DO, Winlaw DS, Ho JWK, Guillemin GJ, Brown MA, Kikuchi K, Thomas PQ, Stocker R, Giannoulatou E, Chapman G, Duncan EL, Sparrow DB, Dunwoodie SL. Shi H, et al. N Engl J Med. 2017 Aug 10;377(6):544-552. doi: 10.1056/NEJMoa1616361. N Engl J Med. 2017. PMID: 28792876 Free article.
Inwardly rectifying potassium channels mediate polymyxin-induced nephrotoxicity.
Lu J, Azad MAK, Moreau JLM, Zhu Y, Jiang X, Tonta M, Lam R, Wickremasinghe H, Zhao J, Wang J, Coleman HA, Formosa LE, Velkov T, Parkington HC, Combes AN, Rosenbluh J, Li J. Lu J, et al. Among authors: moreau jlm. Cell Mol Life Sci. 2022 May 15;79(6):296. doi: 10.1007/s00018-022-04316-z. Cell Mol Life Sci. 2022. PMID: 35570209 Free PMC article.