Chapman G - Search Results

1

Functional genomics and gene-environment interaction highlight the complexity of congenital heart disease caused by Notch pathway variants.

Chapman G, Moreau JLM, I P E, Szot JO, Iyer KR, Shi H, Yam MX, O'Reilly VC, Enriquez A, Greasby JA, Alankarage D, Martin EMMA, Hanna BC, Edwards M, Monger S, Blue GM, Winlaw DS, Ritchie HE, Grieve SM, Giannoulatou E, Sparrow DB, Dunwoodie SL. Chapman G, et al. Hum Mol Genet. 2020 Mar 13;29(4):566-579. doi: 10.1093/hmg/ddz270. Hum Mol Genet. 2020. PMID: 31813956 Free PMC article.

2

Mutation of the LUNATIC FRINGE gene in humans causes spondylocostal dysostosis with a severe vertebral phenotype.

Sparrow DB, Chapman G, Wouters MA, Whittock NV, Ellard S, Fatkin D, Turnpenny PD, Kusumi K, Sillence D, Dunwoodie SL. Sparrow DB, et al. Among authors: chapman g. Am J Hum Genet. 2006 Jan;78(1):28-37. doi: 10.1086/498879. Epub 2005 Nov 16. Am J Hum Genet. 2006. PMID: 16385447 Free PMC article.

3

Disruption of the somitic molecular clock causes abnormal vertebral segmentation.

Sparrow DB, Chapman G, Turnpenny PD, Dunwoodie SL. Sparrow DB, et al. Among authors: chapman g. Birth Defects Res C Embryo Today. 2007 Jun;81(2):93-110. doi: 10.1002/bdrc.20093. Birth Defects Res C Embryo Today. 2007. PMID: 17600782 Review.

4

Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo.

Geffers I, Serth K, Chapman G, Jaekel R, Schuster-Gossler K, Cordes R, Sparrow DB, Kremmer E, Dunwoodie SL, Klein T, Gossler A. Geffers I, et al. Among authors: chapman g. J Cell Biol. 2007 Jul 30;178(3):465-76. doi: 10.1083/jcb.200702009. J Cell Biol. 2007. PMID: 17664336 Free PMC article.

5

Role of Delta-like-3 in mammalian somitogenesis and vertebral column formation.

Chapman G, Dunwoodie SL. Chapman G, et al. Adv Exp Med Biol. 2008;638:95-112. doi: 10.1007/978-0-387-09606-3_5. Adv Exp Med Biol. 2008. PMID: 21038772 Review.

6

Notch inhibition by the ligand DELTA-LIKE 3 defines the mechanism of abnormal vertebral segmentation in spondylocostal dysostosis.

Chapman G, Sparrow DB, Kremmer E, Dunwoodie SL. Chapman G, et al. Hum Mol Genet. 2011 Mar 1;20(5):905-16. doi: 10.1093/hmg/ddq529. Epub 2010 Dec 7. Hum Mol Genet. 2011. PMID: 21147753

7

A cell autonomous role for the Notch ligand Delta-like 3 in αβ T-cell development.

Hoyne GF, Chapman G, Sontani Y, Pursglove SE, Dunwoodie SL. Hoyne GF, et al. Among authors: chapman g. Immunol Cell Biol. 2011 Aug;89(6):696-705. doi: 10.1038/icb.2010.154. Epub 2010 Dec 14. Immunol Cell Biol. 2011. PMID: 21151194

8

Loss of Cited2 causes congenital heart disease by perturbing left-right patterning of the body axis.

Lopes Floro K, Artap ST, Preis JI, Fatkin D, Chapman G, Furtado MB, Harvey RP, Hamada H, Sparrow DB, Dunwoodie SL. Lopes Floro K, et al. Among authors: chapman g. Hum Mol Genet. 2011 Mar 15;20(6):1097-110. doi: 10.1093/hmg/ddq554. Epub 2010 Dec 28. Hum Mol Genet. 2011. PMID: 21224256

9

The mouse notches up another success: understanding the causes of human vertebral malformation.

Sparrow DB, Chapman G, Dunwoodie SL. Sparrow DB, et al. Among authors: chapman g. Mamm Genome. 2011 Aug;22(7-8):362-76. doi: 10.1007/s00335-011-9335-5. Epub 2011 Jun 11. Mamm Genome. 2011. PMID: 21667129 Review.

10

Cooperation between somatic Ikaros and Notch1 mutations at the inception of T-ALL.

Sontani Y, Chapman G, Papathanasiou P, Dunwoodie S, Goodnow CC, Hoyne GF. Sontani Y, et al. Among authors: chapman g. Leuk Res. 2011 Nov;35(11):1512-9. doi: 10.1016/j.leukres.2011.07.024. Epub 2011 Aug 15. Leuk Res. 2011. PMID: 21840596 Free article.

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