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ACVR2B/Fc counteracts chemotherapy-induced loss of muscle and bone mass.
Barreto R, Kitase Y, Matsumoto T, Pin F, Colston KC, Couch KE, O'Connell TM, Couch ME, Bonewald LF, Bonetto A. Barreto R, et al. Among authors: pin f. Sci Rep. 2017 Oct 31;7(1):14470. doi: 10.1038/s41598-017-15040-1. Sci Rep. 2017. PMID: 29089584 Free PMC article.
PDK4 drives metabolic alterations and muscle atrophy in cancer cachexia.
Pin F, Novinger LJ, Huot JR, Harris RA, Couch ME, O'Connell TM, Bonetto A. Pin F, et al. FASEB J. 2019 Jun;33(6):7778-7790. doi: 10.1096/fj.201802799R. Epub 2019 Mar 20. FASEB J. 2019. PMID: 30894018 Free PMC article.
Our data support, for the first time, a direct role for PDK4 in promoting cancer-associated muscle metabolic alterations and skeletal muscle atrophy.-Pin, F., Novinger, L. J., Huot, J. R., Harris, R. A., Couch, M. E., O'Connell, T. M., Bonetto, A. ...
Our data support, for the first time, a direct role for PDK4 in promoting cancer-associated muscle metabolic alterations and skeletal muscle …
73 results