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The human tissue-resident CCR5+ T cell compartment maintains protective and functional properties during inflammation.
Woodward Davis AS, Roozen HN, Dufort MJ, DeBerg HA, Delaney MA, Mair F, Erickson JR, Slichter CK, Berkson JD, Klock AM, Mack M, Lwo Y, Ko A, Brand RM, McGowan I, Linsley PS, Dixon DR, Prlic M. Woodward Davis AS, et al. Among authors: brand rm. Sci Transl Med. 2019 Dec 4;11(521):eaaw8718. doi: 10.1126/scitranslmed.aaw8718. Sci Transl Med. 2019. PMID: 31801887 Free PMC article.
The pharmacokinetics, pharmacodynamics, and mucosal responses to maraviroc-containing pre-exposure prophylaxis regimens in MSM.
McGowan I, Wilkin T, Landovitz RJ, Wu C, Chen Y, Marzinke MA, Hendrix CW, Richardson P, Eshleman SH, Andrade A, Chege W, Anderson PL, McCauley M, Farley J, Mayer KH, Anton P, Brand RM, Cranston RD, Gulick R. McGowan I, et al. Among authors: brand rm. AIDS. 2019 Feb 1;33(2):237-246. doi: 10.1097/QAD.0000000000002038. AIDS. 2019. PMID: 30557160 Free PMC article. Clinical Trial.
Brief Report: Dipyridamole Decreases Gut Mucosal Regulatory T-Cell Frequencies Among People With HIV on Antiretroviral Therapy.
Mallarino-Haeger C, Abebe KZ, Jackson EK, Zyhowski A, Klamar-Blain C, Cyktor JC, Comer D, Brand RM, Gillespie DG, Holleran K, Mellors JW, McGowan I, Riddler SA, Macatangay BJC. Mallarino-Haeger C, et al. Among authors: brand rm. J Acquir Immune Defic Syndr. 2020 Dec 15;85(5):665-669. doi: 10.1097/QAI.0000000000002488. J Acquir Immune Defic Syndr. 2020. PMID: 33177477 Free PMC article. Clinical Trial.
Tofacitinib inhibits inflammatory cytokines from ulcerative colitis and healthy mucosal explants and is associated with pSTAT1/3 reduction in T-cells.
Brand RM, Moore BA, Zyhowski A, Siegel A, Uttam S, Metter EJ, Engstrom J, Brand RE, Biswas N, Whitcomb DC, Binion DG, Schwartz M, McGowan I. Brand RM, et al. Among authors: brand re. Am J Physiol Gastrointest Liver Physiol. 2021 Mar 1;320(3):G396-G410. doi: 10.1152/ajpgi.00383.2020. Epub 2020 Dec 23. Am J Physiol Gastrointest Liver Physiol. 2021. PMID: 33355506 Free PMC article.
A topical rectal douche product containing Q-Griffithsin does not disrupt the epithelial border or alter CD4+ cell distribution in the human rectal mucosa.
Franzén Boger M, Benhach N, Hasselrot T, Brand RM, Rohan LC, Wang L, McGowan I, Edick S, Ho K, Meyn L, Matoba N, Palmer KE, Broliden K, Tjernlund A. Franzén Boger M, et al. Among authors: brand rm. Sci Rep. 2023 May 9;13(1):7547. doi: 10.1038/s41598-023-34107-w. Sci Rep. 2023. PMID: 37161022 Free PMC article.
92 results