Yin YW - Search Results

1

Oxidative damage diminishes mitochondrial DNA polymerase replication fidelity.

Anderson AP, Luo X, Russell W, Yin YW. Anderson AP, et al. Among authors: yin yw. Nucleic Acids Res. 2020 Jan 24;48(2):817-829. doi: 10.1093/nar/gkz1018. Nucleic Acids Res. 2020. PMID: 31799610 Free PMC article.

2

Structural insight into processive human mitochondrial DNA synthesis and disease-related polymerase mutations.

Lee YS, Kennedy WD, Yin YW. Lee YS, et al. Among authors: yin yw. Cell. 2009 Oct 16;139(2):312-24. doi: 10.1016/j.cell.2009.07.050. Cell. 2009. PMID: 19837034 Free PMC article.

3

Each monomer of the dimeric accessory protein for human mitochondrial DNA polymerase has a distinct role in conferring processivity.

Lee YS, Lee S, Demeler B, Molineux IJ, Johnson KA, Yin YW. Lee YS, et al. Among authors: yin yw. J Biol Chem. 2010 Jan 8;285(2):1490-9. doi: 10.1074/jbc.M109.062752. Epub 2009 Oct 26. J Biol Chem. 2010. PMID: 19858216 Free PMC article.

4

A single mutation in human mitochondrial DNA polymerase Pol gammaA affects both polymerization and proofreading activities of only the holoenzyme.

Lee YS, Johnson KA, Molineux IJ, Yin YW. Lee YS, et al. Among authors: yin yw. J Biol Chem. 2010 Sep 3;285(36):28105-16. doi: 10.1074/jbc.M110.122283. Epub 2010 May 31. J Biol Chem. 2010. PMID: 20513922 Free PMC article.

5

Exonuclease of human DNA polymerase gamma disengages its strand displacement function.

He Q, Shumate CK, White MA, Molineux IJ, Yin YW. He Q, et al. Among authors: yin yw. Mitochondrion. 2013 Nov;13(6):592-601. doi: 10.1016/j.mito.2013.08.003. Epub 2013 Aug 30. Mitochondrion. 2013. PMID: 23993955 Free PMC article.

6

Structural basis for processivity and antiviral drug toxicity in human mitochondrial DNA replicase.

Szymanski MR, Kuznetsov VB, Shumate C, Meng Q, Lee YS, Patel G, Patel S, Yin YW. Szymanski MR, et al. Among authors: yin yw. EMBO J. 2015 Jul 14;34(14):1959-70. doi: 10.15252/embj.201591520. Epub 2015 Jun 8. EMBO J. 2015. PMID: 26056153 Free PMC article.

7

Probing the structural and molecular basis of nucleotide selectivity by human mitochondrial DNA polymerase γ.

Sohl CD, Szymanski MR, Mislak AC, Shumate CK, Amiralaei S, Schinazi RF, Anderson KS, Yin YW. Sohl CD, et al. Among authors: yin yw. Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):8596-601. doi: 10.1073/pnas.1421733112. Epub 2015 Jun 29. Proc Natl Acad Sci U S A. 2015. PMID: 26124101 Free PMC article.

8

Transcription yield of fully 2'-modified RNA can be increased by the addition of thermostabilizing mutations to T7 RNA polymerase mutants.

Meyer AJ, Garry DJ, Hall B, Byrom MM, McDonald HG, Yang X, Yin YW, Ellington AD. Meyer AJ, et al. Among authors: yin yw. Nucleic Acids Res. 2015 Sep 3;43(15):7480-8. doi: 10.1093/nar/gkv734. Epub 2015 Jul 24. Nucleic Acids Res. 2015. PMID: 26209133 Free PMC article.

9

The DNA Polymerase Gamma R953C Mutant Is Associated with Antiretroviral Therapy-Induced Mitochondrial Toxicity.

Li M, Mislak AC, Foli Y, Agbosu E, Bose V, Bhandari S, Szymanski MR, Shumate CK, Yin YW, Anderson KS, Paintsil E. Li M, et al. Among authors: yin yw. Antimicrob Agents Chemother. 2016 Aug 22;60(9):5608-11. doi: 10.1128/AAC.00976-16. Print 2016 Sep. Antimicrob Agents Chemother. 2016. PMID: 27381400 Free PMC article.

10

A domain in human EXOG converts apoptotic endonuclease to DNA-repair exonuclease.

Szymanski MR, Yu W, Gmyrek AM, White MA, Molineux IJ, Lee JC, Yin YW. Szymanski MR, et al. Among authors: yin yw. Nat Commun. 2017 May 3;8:14959. doi: 10.1038/ncomms14959. Nat Commun. 2017. PMID: 28466855 Free PMC article.

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