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Page 1
Expression profiling of single cells and patient cohorts identifies multiple immunosuppressive pathways and an altered NK cell phenotype in glioblastoma.
Close HJ, Stead LF, Nsengimana J, Reilly KA, Droop A, Wurdak H, Mathew RK, Corns R, Newton-Bishop J, Melcher AA, Short SC, Cook GP, Wilson EB. Close HJ, et al. Among authors: wurdak h. Clin Exp Immunol. 2020 Apr;200(1):33-44. doi: 10.1111/cei.13403. Epub 2019 Dec 16. Clin Exp Immunol. 2020. PMID: 31784984 Free PMC article.
RAD51 Is a Selective DNA Repair Target to Radiosensitize Glioma Stem Cells.
King HO, Brend T, Payne HL, Wright A, Ward TA, Patel K, Egnuni T, Stead LF, Patel A, Wurdak H, Short SC. King HO, et al. Among authors: wurdak h. Stem Cell Reports. 2017 Jan 10;8(1):125-139. doi: 10.1016/j.stemcr.2016.12.005. Stem Cell Reports. 2017. PMID: 28076755 Free PMC article.
Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade.
Samson A, Scott KJ, Taggart D, West EJ, Wilson E, Nuovo GJ, Thomson S, Corns R, Mathew RK, Fuller MJ, Kottke TJ, Thompson JM, Ilett EJ, Cockle JV, van Hille P, Sivakumar G, Polson ES, Turnbull SJ, Appleton ES, Migneco G, Rose AS, Coffey MC, Beirne DA, Collinson FJ, Ralph C, Alan Anthoney D, Twelves CJ, Furness AJ, Quezada SA, Wurdak H, Errington-Mais F, Pandha H, Harrington KJ, Selby PJ, Vile RG, Griffin SD, Stead LF, Short SC, Melcher AA. Samson A, et al. Among authors: wurdak h. Sci Transl Med. 2018 Jan 3;10(422):eaam7577. doi: 10.1126/scitranslmed.aam7577. Sci Transl Med. 2018. PMID: 29298869 Free PMC article.
KHS101 disrupts energy metabolism in human glioblastoma cells and reduces tumor growth in mice.
Polson ES, Kuchler VB, Abbosh C, Ross EM, Mathew RK, Beard HA, da Silva B, Holding AN, Ballereau S, Chuntharpursat-Bon E, Williams J, Griffiths HBS, Shao H, Patel A, Davies AJ, Droop A, Chumas P, Short SC, Lorger M, Gestwicki JE, Roberts LD, Bon RS, Allison SJ, Zhu S, Markowetz F, Wurdak H. Polson ES, et al. Among authors: wurdak h. Sci Transl Med. 2018 Aug 15;10(454):eaar2718. doi: 10.1126/scitranslmed.aar2718. Sci Transl Med. 2018. PMID: 30111643 Free article.
shRNA-mediated PPARα knockdown in human glioma stem cells reduces in vitro proliferation and inhibits orthotopic xenograft tumour growth.
Haynes HR, Scott HL, Killick-Cole CL, Shaw G, Brend T, Hares KM, Redondo J, Kemp KC, Ballesteros LS, Herman A, Cordero-Llana O, Singleton WG, Mills F, Batstone T, Bulstrode H, Kauppinen RA, Wurdak H, Uney JB, Short SC, Wilkins A, Kurian KM. Haynes HR, et al. Among authors: wurdak h. J Pathol. 2019 Apr;247(4):422-434. doi: 10.1002/path.5201. Epub 2018 Dec 27. J Pathol. 2019. PMID: 30565681 Free PMC article.
Chemically induced neurite-like outgrowth reveals a multicellular network function in patient-derived glioblastoma cells.
da Silva B, Irving BK, Polson ES, Droop A, Griffiths HBS, Mathew RK, Stead LF, Marrison J, Williams C, Williams J, Short SC, Scarcia M, O'Toole PJ, Allison SJ, Mavria G, Wurdak H. da Silva B, et al. Among authors: wurdak h. J Cell Sci. 2019 Oct 10;132(19):jcs228452. doi: 10.1242/jcs.228452. J Cell Sci. 2019. PMID: 31515278 Free article.
Profiling cytotoxic microRNAs in pediatric and adult glioblastoma cells by high-content screening, identification, and validation of miR-1300.
Boissinot M, King H, Adams M, Higgins J, Shaw G, Ward TA, Steele LP, Tams D, Morton R, Polson E, da Silva B, Droop A, Hayes JL, Martin H, Laslo P, Morrison E, Tomlinson DC, Wurdak H, Bond J, Lawler SE, Short SC. Boissinot M, et al. Among authors: wurdak h. Oncogene. 2020 Jul;39(30):5292-5306. doi: 10.1038/s41388-020-1360-y. Epub 2020 Jun 17. Oncogene. 2020. PMID: 32555332 Free PMC article.
37 results