Kahle PJ - Search Results

1

Multiple distinct pathways lead to hyperubiquitylated insoluble TDP-43 protein independent of its translocation into stress granules.

Hans F, Glasebach H, Kahle PJ. Hans F, et al. Among authors: kahle pj. J Biol Chem. 2020 Jan 17;295(3):673-689. doi: 10.1074/jbc.RA119.010617. Epub 2019 Nov 28. J Biol Chem. 2020. PMID: 31780563 Free PMC article.

2

Oxidizable residues mediating protein stability and cytoprotective interaction of DJ-1 with apoptosis signal-regulating kinase 1.

Waak J, Weber SS, Görner K, Schall C, Ichijo H, Stehle T, Kahle PJ. Waak J, et al. Among authors: kahle pj. J Biol Chem. 2009 May 22;284(21):14245-57. doi: 10.1074/jbc.M806902200. Epub 2009 Mar 16. J Biol Chem. 2009. PMID: 19293155 Free PMC article.

3

UBE2E ubiquitin-conjugating enzymes and ubiquitin isopeptidase Y regulate TDP-43 protein ubiquitination.

Hans F, Fiesel FC, Strong JC, Jäckel S, Rasse TM, Geisler S, Springer W, Schulz JB, Voigt A, Kahle PJ. Hans F, et al. Among authors: kahle pj. J Biol Chem. 2014 Jul 4;289(27):19164-79. doi: 10.1074/jbc.M114.561704. Epub 2014 May 13. J Biol Chem. 2014. PMID: 24825905 Free PMC article.

4

Identification and characterization of ubiquitinylation sites in TAR DNA-binding protein of 43 kDa (TDP-43).

Hans F, Eckert M, von Zweydorf F, Gloeckner CJ, Kahle PJ. Hans F, et al. Among authors: kahle pj. J Biol Chem. 2018 Oct 12;293(41):16083-16099. doi: 10.1074/jbc.RA118.003440. Epub 2018 Aug 17. J Biol Chem. 2018. PMID: 30120199 Free PMC article.

5

Monitoring α-synuclein multimerization in vivo.

Prasad V, Wasser Y, Hans F, Goswami A, Katona I, Outeiro TF, Kahle PJ, Schulz JB, Voigt A. Prasad V, et al. Among authors: kahle pj. FASEB J. 2019 Feb;33(2):2116-2131. doi: 10.1096/fj.201800148RRR. Epub 2018 Sep 25. FASEB J. 2019. PMID: 30252534

6

Ubiquitin-specific protease USP36 knockdown impairs Parkin-dependent mitophagy via downregulation of Beclin-1-associated autophagy-related ATG14L.

Geisler S, Jäger L, Golombek S, Nakanishi E, Hans F, Casadei N, Terradas AL, Linnemann C, Kahle PJ. Geisler S, et al. Among authors: kahle pj. Exp Cell Res. 2019 Nov 15;384(2):111641. doi: 10.1016/j.yexcr.2019.111641. Epub 2019 Sep 21. Exp Cell Res. 2019. PMID: 31550441

7

Regulation of mitochondrial cargo-selective autophagy by posttranslational modifications.

Lechado Terradas A, Zittlau KI, Macek B, Fraiberg M, Elazar Z, Kahle PJ. Lechado Terradas A, et al. Among authors: kahle pj. J Biol Chem. 2021 Nov;297(5):101339. doi: 10.1016/j.jbc.2021.101339. Epub 2021 Oct 22. J Biol Chem. 2021. PMID: 34688664 Free PMC article. Review.

8

Sirtuin-1 sensitive lysine-136 acetylation drives phase separation and pathological aggregation of TDP-43.

Garcia Morato J, Hans F, von Zweydorf F, Feederle R, Elsässer SJ, Skodras AA, Gloeckner CJ, Buratti E, Neumann M, Kahle PJ. Garcia Morato J, et al. Among authors: kahle pj. Nat Commun. 2022 Mar 9;13(1):1223. doi: 10.1038/s41467-022-28822-7. Nat Commun. 2022. PMID: 35264561 Free PMC article.

9

Parkin protects against tyrosinase-mediated dopamine neurotoxicity by suppressing stress-activated protein kinase pathways.

Hasegawa T, Treis A, Patenge N, Fiesel FC, Springer W, Kahle PJ. Hasegawa T, et al. Among authors: kahle pj. J Neurochem. 2008 Jun;105(5):1700-15. doi: 10.1111/j.1471-4159.2008.05277.x. Epub 2008 Feb 4. J Neurochem. 2008. PMID: 18248610 Free article.

10

DJ-1 and prevention of oxidative stress in Parkinson's disease and other age-related disorders.

Kahle PJ, Waak J, Gasser T. Kahle PJ, et al. Free Radic Biol Med. 2009 Nov 15;47(10):1354-61. doi: 10.1016/j.freeradbiomed.2009.08.003. Epub 2009 Aug 14. Free Radic Biol Med. 2009. PMID: 19686841 Review.

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