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The anti-IgE mAb omalizumab induces adverse reactions by engaging Fcγ receptors.
Balbino B, Herviou P, Godon O, Stackowicz J, Goff OR, Iannascoli B, Sterlin D, Brûlé S, Millot GA, Harris FM, Voronina VA, Nadeau KC, Macdonald LE, Murphy AJ, Bruhns P, Reber LL. Balbino B, et al. Among authors: nadeau kc. J Clin Invest. 2020 Mar 2;130(3):1330-1335. doi: 10.1172/JCI129697. J Clin Invest. 2020. PMID: 31770111 Free PMC article.
Selective ablation of mast cells or basophils reduces peanut-induced anaphylaxis in mice.
Reber LL, Marichal T, Mukai K, Kita Y, Tokuoka SM, Roers A, Hartmann K, Karasuyama H, Nadeau KC, Tsai M, Galli SJ. Reber LL, et al. Among authors: nadeau kc. J Allergy Clin Immunol. 2013 Oct;132(4):881-8.e1-11. doi: 10.1016/j.jaci.2013.06.008. Epub 2013 Aug 1. J Allergy Clin Immunol. 2013. PMID: 23915716 Free PMC article.
Combining anti-IgE with oral immunotherapy.
Lin C, Lee IT, Sampath V, Dinakar C, DeKruyff RH, Schneider LC, Nadeau KC. Lin C, et al. Among authors: nadeau kc. Pediatr Allergy Immunol. 2017 Nov;28(7):619-627. doi: 10.1111/pai.12767. Epub 2017 Sep 7. Pediatr Allergy Immunol. 2017. PMID: 28782296 Review.
Widespread monoclonal IgE antibody convergence to an immunodominant, proanaphylactic Ara h 2 epitope in peanut allergy.
Croote D, Wong JJW, Pecalvel C, Leveque E, Casanovas N, Kamphuis JBJ, Creeks P, Romero J, Sohail S, Bedinger D, Nadeau KC, Chinthrajah RS, Reber LL, Lowman HB. Croote D, et al. Among authors: nadeau kc. J Allergy Clin Immunol. 2024 Jan;153(1):182-192.e7. doi: 10.1016/j.jaci.2023.08.035. Epub 2023 Sep 23. J Allergy Clin Immunol. 2024. PMID: 37748654 Free PMC article.
Anti-IgE treatment with oral immunotherapy in multifood allergic participants: a double-blind, randomised, controlled trial.
Andorf S, Purington N, Block WM, Long AJ, Tupa D, Brittain E, Rudman Spergel A, Desai M, Galli SJ, Nadeau KC, Chinthrajah RS. Andorf S, et al. Among authors: nadeau kc. Lancet Gastroenterol Hepatol. 2018 Feb;3(2):85-94. doi: 10.1016/S2468-1253(17)30392-8. Epub 2017 Dec 12. Lancet Gastroenterol Hepatol. 2018. PMID: 29242014 Free PMC article. Clinical Trial.
444 results