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Stalled developmental programs at the root of pediatric brain tumors.
Jessa S, Blanchet-Cohen A, Krug B, Vladoiu M, Coutelier M, Faury D, Poreau B, De Jay N, Hébert S, Monlong J, Farmer WT, Donovan LK, Hu Y, McConechy MK, Cavalli FMG, Mikael LG, Ellezam B, Richer M, Allaire A, Weil AG, Atkinson J, Farmer JP, Dudley RWR, Larouche V, Crevier L, Albrecht S, Filbin MG, Sartelet H, Lutz PE, Nagy C, Turecki G, Costantino S, Dirks PB, Murai KK, Bourque G, Ragoussis J, Garzia L, Taylor MD, Jabado N, Kleinman CL. Jessa S, et al. Among authors: murai kk. Nat Genet. 2019 Dec;51(12):1702-1713. doi: 10.1038/s41588-019-0531-7. Epub 2019 Nov 25. Nat Genet. 2019. PMID: 31768071 Free PMC article.
Neurons diversify astrocytes in the adult brain through sonic hedgehog signaling.
Farmer WT, Abrahamsson T, Chierzi S, Lui C, Zaelzer C, Jones EV, Bally BP, Chen GG, Théroux JF, Peng J, Bourque CW, Charron F, Ernst C, Sjöström PJ, Murai KK. Farmer WT, et al. Among authors: murai kk. Science. 2016 Feb 19;351(6275):849-54. doi: 10.1126/science.aab3103. Science. 2016. PMID: 26912893
Resolving Astrocyte Heterogeneity in the CNS.
Farmer WT, Murai K. Farmer WT, et al. Front Cell Neurosci. 2017 Sep 27;11:300. doi: 10.3389/fncel.2017.00300. eCollection 2017. Front Cell Neurosci. 2017. PMID: 29021743 Free PMC article. Review.
Human iPSC-derived Down syndrome astrocytes display genome-wide perturbations in gene expression, an altered adhesion profile, and increased cellular dynamics.
Ponroy Bally B, Farmer WT, Jones EV, Jessa S, Kacerovsky JB, Mayran A, Peng H, Lefebvre JL, Drouin J, Hayer A, Ernst C, Murai KK. Ponroy Bally B, et al. Among authors: murai kk. Hum Mol Genet. 2020 Mar 27;29(5):785-802. doi: 10.1093/hmg/ddaa003. Hum Mol Genet. 2020. PMID: 31943018 Free PMC article.
Characterization of Vimentin-Immunoreactive Astrocytes in the Human Brain.
O'Leary LA, Davoli MA, Belliveau C, Tanti A, Ma JC, Farmer WT, Turecki G, Murai KK, Mechawar N. O'Leary LA, et al. Among authors: murai kk. Front Neuroanat. 2020 Jul 30;14:31. doi: 10.3389/fnana.2020.00031. eCollection 2020. Front Neuroanat. 2020. PMID: 32848635 Free PMC article.
74 results