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The Hepatokine TSK does not affect brown fat thermogenic capacity, body weight gain, and glucose homeostasis.
Mouchiroud M, Camiré É, Aldow M, Caron A, Jubinville É, Turcotte L, Kaci I, Beaulieu MJ, Roy C, Labbé SM, Varin TV, Gélinas Y, Lamothe J, Trottier J, Mitchell PL, Guénard F, Festuccia WT, Joubert P, Rose CF, Karvellas CJ, Barbier O, Morissette MC, Marette A, Laplante M. Mouchiroud M, et al. Among authors: festuccia wt. Mol Metab. 2019 Dec;30:184-191. doi: 10.1016/j.molmet.2019.09.014. Epub 2019 Oct 4. Mol Metab. 2019. PMID: 31767170 Free PMC article.
11beta-HSD1 inhibition improves triglyceridemia through reduced liver VLDL secretion and partitions lipids toward oxidative tissues.
Berthiaume M, Laplante M, Festuccia WT, Cianflone K, Turcotte LP, Joanisse DR, Olivecrona G, Thieringer R, Deshaies Y. Berthiaume M, et al. Among authors: festuccia wt. Am J Physiol Endocrinol Metab. 2007 Oct;293(4):E1045-52. doi: 10.1152/ajpendo.00276.2007. Epub 2007 Jul 31. Am J Physiol Endocrinol Metab. 2007. PMID: 17666487 Free article.
Peroxisome proliferator-activated receptor-gamma-mediated positive energy balance in the rat is associated with reduced sympathetic drive to adipose tissues and thyroid status.
Festuccia WT, Oztezcan S, Laplante M, Berthiaume M, Michel C, Dohgu S, Denis RG, Brito MN, Brito NA, Miller DS, Banks WA, Bartness TJ, Richard D, Deshaies Y. Festuccia WT, et al. Endocrinology. 2008 May;149(5):2121-30. doi: 10.1210/en.2007-1553. Epub 2008 Jan 24. Endocrinology. 2008. PMID: 18218698
99 results