Thornton DJ - Search Results

1

The MUC5B mucin polymer is dominated by repeating structural motifs and its topology is regulated by calcium and pH.

Hughes GW, Ridley C, Collins R, Roseman A, Ford R, Thornton DJ. Hughes GW, et al. Among authors: thornton dj. Sci Rep. 2019 Nov 22;9(1):17350. doi: 10.1038/s41598-019-53768-0. Sci Rep. 2019. PMID: 31758042 Free PMC article.

2

Identification of two glycoforms of the MUC5B mucin in human respiratory mucus. Evidence for a cysteine-rich sequence repeated within the molecule.

Thornton DJ, Howard M, Khan N, Sheehan JK. Thornton DJ, et al. J Biol Chem. 1997 Apr 4;272(14):9561-6. doi: 10.1074/jbc.272.14.9561. J Biol Chem. 1997. PMID: 9083100 Free article.

3

Physical characterization of a low-charge glycoform of the MUC5B mucin comprising the gel-phase of an asthmatic respiratory mucous plug.

Sheehan JK, Howard M, Richardson PS, Longwill T, Thornton DJ. Sheehan JK, et al. Among authors: thornton dj. Biochem J. 1999 Mar 1;338 ( Pt 2)(Pt 2):507-13. Biochem J. 1999. PMID: 10024529 Free PMC article.

4

Identification of a nonmucin glycoprotein (gp-340) from a purified respiratory mucin preparation: evidence for an association involving the MUC5B mucin.

Thornton DJ, Davies JR, Kirkham S, Gautrey A, Khan N, Richardson PS, Sheehan JK. Thornton DJ, et al. Glycobiology. 2001 Nov;11(11):969-77. doi: 10.1093/glycob/11.11.969. Glycobiology. 2001. PMID: 11744631

5

Heterogeneity of airways mucus: variations in the amounts and glycoforms of the major oligomeric mucins MUC5AC and MUC5B.

Kirkham S, Sheehan JK, Knight D, Richardson PS, Thornton DJ. Kirkham S, et al. Among authors: thornton dj. Biochem J. 2002 Feb 1;361(Pt 3):537-46. doi: 10.1042/0264-6021:3610537. Biochem J. 2002. PMID: 11802783 Free PMC article.

6

Concentrated solutions of salivary MUC5B mucin do not replicate the gel-forming properties of saliva.

Raynal BD, Hardingham TE, Thornton DJ, Sheehan JK. Raynal BD, et al. Among authors: thornton dj. Biochem J. 2002 Mar 1;362(Pt 2):289-96. doi: 10.1042/0264-6021:3620289. Biochem J. 2002. PMID: 11853536 Free PMC article.

7

Calcium-dependent protein interactions in MUC5B provide reversible cross-links in salivary mucus.

Raynal BD, Hardingham TE, Sheehan JK, Thornton DJ. Raynal BD, et al. Among authors: thornton dj. J Biol Chem. 2003 Aug 1;278(31):28703-10. doi: 10.1074/jbc.M304632200. Epub 2003 May 19. J Biol Chem. 2003. PMID: 12756239 Free article.

8

Muc5b and Muc5ac are the major oligomeric mucins in equine airway mucus.

Rousseau K, Kirkham S, McKane S, Newton R, Clegg P, Thornton DJ. Rousseau K, et al. Among authors: thornton dj. Am J Physiol Lung Cell Mol Physiol. 2007 Jun;292(6):L1396-404. doi: 10.1152/ajplung.00444.2006. Epub 2007 Feb 9. Am J Physiol Lung Cell Mol Physiol. 2007. PMID: 17293373 Free article.

9

MUC5B is the major mucin in the gel phase of sputum in chronic obstructive pulmonary disease.

Kirkham S, Kolsum U, Rousseau K, Singh D, Vestbo J, Thornton DJ. Kirkham S, et al. Among authors: thornton dj. Am J Respir Crit Care Med. 2008 Nov 15;178(10):1033-9. doi: 10.1164/rccm.200803-391OC. Epub 2008 Sep 5. Am J Respir Crit Care Med. 2008. PMID: 18776153 Free PMC article.

10

TGF-β₂ decreases baseline and IL-13-stimulated mucin production by primary human bronchial epithelial cells.

Harrop CA, Gore RB, Evans CM, Thornton DJ, Herrick SE. Harrop CA, et al. Among authors: thornton dj. Exp Lung Res. 2013 Feb;39(1):39-47. doi: 10.3109/01902148.2012.748854. Epub 2012 Dec 18. Exp Lung Res. 2013. PMID: 23249391 Free article.

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