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A divergent transcriptional landscape underpins the development and functional branching of MAIT cells.
Koay HF, Su S, Amann-Zalcenstein D, Daley SR, Comerford I, Miosge L, Whyte CE, Konstantinov IE, d'Udekem Y, Baldwin T, Hickey PF, Berzins SP, Mak JYW, Sontani Y, Roots CM, Sidwell T, Kallies A, Chen Z, Nüssing S, Kedzierska K, Mackay LK, McColl SR, Deenick EK, Fairlie DP, McCluskey J, Goodnow CC, Ritchie ME, Belz GT, Naik SH, Pellicci DG, Godfrey DI. Koay HF, et al. Among authors: nussing s. Sci Immunol. 2019 Nov 22;4(41):eaay6039. doi: 10.1126/sciimmunol.aay6039. Sci Immunol. 2019. PMID: 31757835 Free PMC article.
The role of CD27 in anti-viral T-cell immunity.
Grant EJ, Nüssing S, Sant S, Clemens EB, Kedzierska K. Grant EJ, et al. Among authors: nussing s. Curr Opin Virol. 2017 Feb;22:77-88. doi: 10.1016/j.coviro.2016.12.001. Epub 2017 Jan 12. Curr Opin Virol. 2017. PMID: 28086150 Review.
Innate and adaptive T cells in influenza disease.
Nüssing S, Sant S, Koutsakos M, Subbarao K, Nguyen THO, Kedzierska K. Nüssing S, et al. Front Med. 2018 Feb;12(1):34-47. doi: 10.1007/s11684-017-0606-8. Epub 2018 Jan 20. Front Med. 2018. PMID: 29352371 Review.
Circulating TFH cells, serological memory, and tissue compartmentalization shape human influenza-specific B cell immunity.
Koutsakos M, Wheatley AK, Loh L, Clemens EB, Sant S, Nüssing S, Fox A, Chung AW, Laurie KL, Hurt AC, Rockman S, Lappas M, Loudovaris T, Mannering SI, Westall GP, Elliot M, Tangye SG, Wakim LM, Kent SJ, Nguyen THO, Kedzierska K. Koutsakos M, et al. Among authors: nussing s. Sci Transl Med. 2018 Feb 14;10(428):eaan8405. doi: 10.1126/scitranslmed.aan8405. Sci Transl Med. 2018. PMID: 29444980
MAIT cells contribute to protection against lethal influenza infection in vivo.
van Wilgenburg B, Loh L, Chen Z, Pediongco TJ, Wang H, Shi M, Zhao Z, Koutsakos M, Nüssing S, Sant S, Wang Z, D'Souza C, Jia X, Almeida CF, Kostenko L, Eckle SBG, Meehan BS, Kallies A, Godfrey DI, Reading PC, Corbett AJ, McCluskey J, Klenerman P, Kedzierska K, Hinks TSC. van Wilgenburg B, et al. Among authors: nussing s. Nat Commun. 2018 Nov 9;9(1):4706. doi: 10.1038/s41467-018-07207-9. Nat Commun. 2018. PMID: 30413689 Free PMC article.
Divergent SATB1 expression across human life span and tissue compartments.
Nüssing S, Koay HF, Sant S, Loudovaris T, Mannering SI, Lappas M, D Udekem Y, Konstantinov IE, Berzins SP, Rimmelzwaan GF, Turner SJ, Clemens EB, Godfrey DI, Nguyen TH, Kedzierska K. Nüssing S, et al. Immunol Cell Biol. 2019 May;97(5):498-511. doi: 10.1111/imcb.12233. Epub 2019 Feb 25. Immunol Cell Biol. 2019. PMID: 30803026 Free PMC article.
Antigen-driven EGR2 expression is required for exhausted CD8+ T cell stability and maintenance.
Wagle MV, Vervoort SJ, Kelly MJ, Van Der Byl W, Peters TJ, Martin BP, Martelotto LG, Nüssing S, Ramsbottom KM, Torpy JR, Knight D, Reading S, Thia K, Miosge LA, Howard DR, Gloury R, Gabriel SS, Utzschneider DT, Oliaro J, Powell JD, Luciani F, Trapani JA, Johnstone RW, Kallies A, Goodnow CC, Parish IA. Wagle MV, et al. Among authors: nussing s. Nat Commun. 2021 May 13;12(1):2782. doi: 10.1038/s41467-021-23044-9. Nat Commun. 2021. PMID: 33986293 Free PMC article.
SATB1 ensures appropriate transcriptional programs within naïve CD8+ T cells.
Nüssing S, Miosge LA, Lee K, Olshansky M, Barugahare A, Roots CM, Sontani Y, Day EB, Koutsakos M, Kedzierska K, Goodnow CC, Russ BE, Daley SR, Turner SJ. Nüssing S, et al. Immunol Cell Biol. 2022 Sep;100(8):636-652. doi: 10.1111/imcb.12566. Epub 2022 Jul 13. Immunol Cell Biol. 2022. PMID: 35713361 Free PMC article.
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