Lomas DA - Search Results

1

Calcium signalling in mammalian cell lines expressing wild type and mutant human α1-Antitrypsin.

Malintan NT, Buckingham SD, Lomas DA, Sattelle DB. Malintan NT, et al. Among authors: lomas da. Sci Rep. 2019 Nov 21;9(1):17293. doi: 10.1038/s41598-019-53535-1. Sci Rep. 2019. PMID: 31754242 Free PMC article.

2

Alzheimer's disease: insights from Drosophila melanogaster models.

Moloney A, Sattelle DB, Lomas DA, Crowther DC. Moloney A, et al. Among authors: lomas da. Trends Biochem Sci. 2010 Apr;35(4):228-35. doi: 10.1016/j.tibs.2009.11.004. Epub 2009 Dec 25. Trends Biochem Sci. 2010. PMID: 20036556 Free PMC article. Review.

3

The TRiC/CCT chaperone is implicated in Alzheimer's disease based on patient GWAS and an RNAi screen in Aβ-expressing Caenorhabditis elegans.

Khabirova E, Moloney A, Marciniak SJ, Williams J, Lomas DA, Oliver SG, Favrin G, Sattelle DB, Crowther DC. Khabirova E, et al. Among authors: lomas da. PLoS One. 2014 Jul 31;9(7):e102985. doi: 10.1371/journal.pone.0102985. eCollection 2014. PLoS One. 2014. PMID: 25080104 Free PMC article.

4

Update on alpha-1 antitrypsin deficiency: New therapies.

Lomas DA, Hurst JR, Gooptu B. Lomas DA, et al. J Hepatol. 2016 Aug;65(2):413-24. doi: 10.1016/j.jhep.2016.03.010. Epub 2016 Mar 29. J Hepatol. 2016. PMID: 27034252 Review.

5

α1-Antitrypsin deficiency.

Greene CM, Marciniak SJ, Teckman J, Ferrarotti I, Brantly ML, Lomas DA, Stoller JK, McElvaney NG. Greene CM, et al. Among authors: lomas da. Nat Rev Dis Primers. 2016 Jul 28;2:16051. doi: 10.1038/nrdp.2016.51. Nat Rev Dis Primers. 2016. PMID: 27465791 Review.

6

The endoplasmic reticulum remains functionally connected by vesicular transport after its fragmentation in cells expressing Z-α1-antitrypsin.

Dickens JA, Ordóñez A, Chambers JE, Beckett AJ, Patel V, Malzer E, Dominicus CS, Bradley J, Peden AA, Prior IA, Lomas DA, Marciniak SJ. Dickens JA, et al. Among authors: lomas da. FASEB J. 2016 Dec;30(12):4083-4097. doi: 10.1096/fj.201600430R. Epub 2016 Sep 6. FASEB J. 2016. PMID: 27601439 Free PMC article.

7

Liver: Taking out the JuNK to treat α1-antitrypsin deficiency.

Rashid ST, Lomas DA. Rashid ST, et al. Among authors: lomas da. Nat Rev Gastroenterol Hepatol. 2017 Apr;14(4):201-202. doi: 10.1038/nrgastro.2017.22. Epub 2017 Mar 8. Nat Rev Gastroenterol Hepatol. 2017. PMID: 28270697 No abstract available.

8

An automated high-throughput system for phenotypic screening of chemical libraries on C. elegans and parasitic nematodes.

Partridge FA, Brown AE, Buckingham SD, Willis NJ, Wynne GM, Forman R, Else KJ, Morrison AA, Matthews JB, Russell AJ, Lomas DA, Sattelle DB. Partridge FA, et al. Among authors: lomas da. Int J Parasitol Drugs Drug Resist. 2018 Apr;8(1):8-21. doi: 10.1016/j.ijpddr.2017.11.004. Epub 2017 Dec 2. Int J Parasitol Drugs Drug Resist. 2018. PMID: 29223747 Free PMC article.

9

Heteropolymerization of α-1-antitrypsin mutants in cell models mimicking heterozygosity.

Laffranchi M, Berardelli R, Ronzoni R, Lomas DA, Fra A. Laffranchi M, et al. Among authors: lomas da. Hum Mol Genet. 2018 May 15;27(10):1785-1793. doi: 10.1093/hmg/ddy090. Hum Mol Genet. 2018. PMID: 29538751

10

C. elegans expressing D76N β₂-microglobulin: a model for in vivo screening of drug candidates targeting amyloidosis.

Faravelli G, Raimondi S, Marchese L, Partridge FA, Soria C, Mangione PP, Canetti D, Perni M, Aprile FA, Zorzoli I, Di Schiavi E, Lomas DA, Bellotti V, Sattelle DB, Giorgetti S. Faravelli G, et al. Among authors: lomas da. Sci Rep. 2019 Dec 27;9(1):19960. doi: 10.1038/s41598-019-56498-5. Sci Rep. 2019. PMID: 31882874 Free PMC article.

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