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An automated high-throughput system for phenotypic screening of chemical libraries on C. elegans and parasitic nematodes.
Partridge FA, Brown AE, Buckingham SD, Willis NJ, Wynne GM, Forman R, Else KJ, Morrison AA, Matthews JB, Russell AJ, Lomas DA, Sattelle DB. Partridge FA, et al. Among authors: buckingham sd. Int J Parasitol Drugs Drug Resist. 2018 Apr;8(1):8-21. doi: 10.1016/j.ijpddr.2017.11.004. Epub 2017 Dec 2. Int J Parasitol Drugs Drug Resist. 2018. PMID: 29223747 Free PMC article.
The fungal alkaloid Okaramine-B activates an L-glutamate-gated chloride channel from Ixodes scapularis, a tick vector of Lyme disease.
Furutani S, Ihara M, Lees K, Buckingham SD, Partridge FA, David JA, Patel R, Warchal S, Mellor IR, Matsuda K, Sattelle DB. Furutani S, et al. Among authors: buckingham sd. Int J Parasitol Drugs Drug Resist. 2018 Aug;8(2):350-360. doi: 10.1016/j.ijpddr.2018.06.001. Epub 2018 Jun 4. Int J Parasitol Drugs Drug Resist. 2018. PMID: 29957333 Free PMC article.
85 results