Pacifico S - Search Results

1

Serum beta-secretase 1 (BACE1) activity as candidate biomarker for late-onset Alzheimer's disease.

Cervellati C, Trentini A, Rosta V, Passaro A, Bosi C, Sanz JM, Bonazzi S, Pacifico S, Seripa D, Valacchi G, Guerini R, Zuliani G. Cervellati C, et al. Among authors: pacifico s. Geroscience. 2020 Feb;42(1):159-167. doi: 10.1007/s11357-019-00127-6. Epub 2019 Nov 19. Geroscience. 2020. PMID: 31745860 Free PMC article.

2

Increased blood BACE1 activity as a potential common pathogenic factor of vascular dementia and late onset Alzheimer's disease.

Zuliani G, Trentini A, Rosta V, Guerrini R, Pacifico S, Bonazzi S, Guiotto A, Passaro A, Seripa D, Valacchi G, Cervellati C. Zuliani G, et al. Among authors: pacifico s. Sci Rep. 2020 Sep 11;10(1):14980. doi: 10.1038/s41598-020-72168-3. Sci Rep. 2020. PMID: 32917964 Free PMC article.

3

Serum beta-secretase 1 (BACE1) activity increases in patients with mild cognitive impairment.

Zuliani G, Trentini A, Brombo G, Rosta V, Guasti P, Romagnoli T, Polastri M, Marabini L, Pedrini D, Pistolesi C, Pacifico S, Guerrini R, Seripa D, Cervellati C. Zuliani G, et al. Among authors: pacifico s. J Neurochem. 2021 Nov;159(3):629-637. doi: 10.1111/jnc.15513. Epub 2021 Oct 3. J Neurochem. 2021. PMID: 34534363 Free article.

4

Antagonistic Activity of Naphthoquinone-Based Hybrids toward Amyloids Associated with Alzheimer's Disease and Type-2 Diabetes.

Paul A, Viswanathan GK, Mahapatra S, Balboni G, Pacifico S, Gazit E, Segal D. Paul A, et al. Among authors: pacifico s. ACS Chem Neurosci. 2019 Aug 21;10(8):3510-3520. doi: 10.1021/acschemneuro.9b00123. Epub 2019 Jul 8. ACS Chem Neurosci. 2019. PMID: 31282646

5

In vitro and in vivo pharmacological characterization of a neuropeptide S tetrabranched derivative.

Ruzza C, Rizzi A, Malfacini D, Pulga A, Pacifico S, Salvadori S, Trapella C, Reinscheid RK, Calo G, Guerrini R. Ruzza C, et al. Among authors: pacifico s. Pharmacol Res Perspect. 2015 Feb;3(1):e00108. doi: 10.1002/prp2.108. Epub 2015 Jan 5. Pharmacol Res Perspect. 2015. PMID: 25692025 Free PMC article.

6

Intracellular quantitative detection of human thymidylate synthase engagement with an unconventional inhibitor using tetracysteine-diarsenical-probe technology.

Ponterini G, Martello A, Pavesi G, Lauriola A, Luciani R, Santucci M, Pelà M, Gozzi G, Pacifico S, Guerrini R, Marverti G, Costi MP, D'Arca D. Ponterini G, et al. Among authors: pacifico s. Sci Rep. 2016 Jun 2;6:27198. doi: 10.1038/srep27198. Sci Rep. 2016. PMID: 27250901 Free PMC article.

7

Structure- and conformation-activity studies of nociceptin/orphanin FQ receptor dimeric ligands.

Pacifico S, Carotenuto A, Brancaccio D, Novellino E, Marzola E, Ferrari F, Cerlesi MC, Trapella C, Preti D, Salvadori S, Calò G, Guerrini R. Pacifico S, et al. Sci Rep. 2017 Apr 6;7:45817. doi: 10.1038/srep45817. Sci Rep. 2017. PMID: 28383520 Free PMC article.

8

Urotensin-II peptidomimetic incorporating a non-reducible 1,5-triazole disulfide bond reveals a pseudo-irreversible covalent binding mechanism to the urotensin G-protein coupled receptor.

Pacifico S, Kerckhoffs A, Fallow AJ, Foreman RE, Guerrini R, McDonald J, Lambert DG, Jamieson AG. Pacifico S, et al. Org Biomol Chem. 2017 May 31;15(21):4704-4710. doi: 10.1039/c7ob00959c. Org Biomol Chem. 2017. PMID: 28524918 Free article.

9

A diastereoselective synthesis of Cebranopadol, a novel analgesic showing NOP/mu mixed agonism.

Fantinati A, Bianco S, Guerrini R, Salvadori S, Pacifico S, Cerlesi MC, Calo G, Trapella C. Fantinati A, et al. Among authors: pacifico s. Sci Rep. 2017 May 25;7(1):2416. doi: 10.1038/s41598-017-02502-9. Sci Rep. 2017. PMID: 28546566 Free PMC article.

10

Peptide welding technology - A simple strategy for generating innovative ligands for G protein coupled receptors.

Calo' G, Rizzi A, Ruzza C, Ferrari F, Pacifico S, Gavioli EC, Salvadori S, Guerrini R. Calo' G, et al. Among authors: pacifico s. Peptides. 2018 Jan;99:195-204. doi: 10.1016/j.peptides.2017.10.004. Epub 2017 Oct 13. Peptides. 2018. PMID: 29031796 Review.

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