Potter BVL - Search Results

1

Nonsteroidal sulfamate derivatives as new therapeutic approaches for Neurofibromatosis 2 (NF2).

Shen YC, Arellano-Garcia C, Menjivar RE, Jewett EM, Dohle W, Karchugina S, Chernoff J, Potter BVL, Barald KF. Shen YC, et al. Among authors: potter bvl. BMC Pharmacol Toxicol. 2019 Nov 15;20(1):67. doi: 10.1186/s40360-019-0369-8. BMC Pharmacol Toxicol. 2019. PMID: 31730023 Free PMC article.

2

Synthesis, antitubulin, and antiproliferative SAR of analogues of 2-methoxyestradiol-3,17-O,O-bis-sulfamate.

Jourdan F, Leese MP, Dohle W, Hamel E, Ferrandis E, Newman SP, Purohit A, Reed MJ, Potter BV. Jourdan F, et al. J Med Chem. 2010 Apr 8;53(7):2942-51. doi: 10.1021/jm9018806. J Med Chem. 2010. PMID: 20225862

3

Structure-activity relationships of C-17-substituted estratriene-3-O-sulfamates as anticancer agents.

Jourdan F, Leese MP, Dohle W, Ferrandis E, Newman SP, Chander S, Purohit A, Potter BV. Jourdan F, et al. J Med Chem. 2011 Jul 14;54(13):4863-79. doi: 10.1021/jm200483x. Epub 2011 Jun 9. J Med Chem. 2011. PMID: 21604672

4

Tetrahydroisoquinolinone-based steroidomimetic and chimeric microtubule disruptors.

Leese MP, Jourdan FL, Major MR, Dohle W, Hamel E, Ferrandis E, Fiore A, Kasprzyk PG, Potter BV. Leese MP, et al. ChemMedChem. 2014 Jan;9(1):85-108, 1. doi: 10.1002/cmdc.201300261. Epub 2013 Oct 9. ChemMedChem. 2014. PMID: 24124095 Free PMC article.

5

Synthesis, antitubulin, and antiproliferative SAR of C3/C1-substituted tetrahydroisoquinolines.

Dohle W, Leese MP, Jourdan FL, Major MR, Bai R, Hamel E, Ferrandis E, Kasprzyk PG, Fiore A, Newman SP, Purohit A, Potter BV. Dohle W, et al. ChemMedChem. 2014 Feb;9(2):350-70. doi: 10.1002/cmdc.201300412. Epub 2014 Jan 16. ChemMedChem. 2014. PMID: 24436228

6

Synthesis, anti-tubulin and antiproliferative SAR of steroidomimetic dihydroisoquinolinones.

Leese MP, Jourdan FL, Major MR, Dohle W, Thomas MP, Hamel E, Ferrandis E, Mahon MF, Newman SP, Purohit A, Potter BV. Leese MP, et al. ChemMedChem. 2014 Apr;9(4):798-812. doi: 10.1002/cmdc.201400017. Epub 2014 Mar 5. ChemMedChem. 2014. PMID: 24596315 Free PMC article.

7

Optimisation of tetrahydroisoquinoline-based chimeric microtubule disruptors.

Dohle W, Leese MP, Jourdan FL, Chapman CJ, Hamel E, Ferrandis E, Potter BV. Dohle W, et al. ChemMedChem. 2014 Aug;9(8):1783-93. doi: 10.1002/cmdc.201402025. Epub 2014 May 12. ChemMedChem. 2014. PMID: 24819406 Free PMC article.

8

Discovery and Development of the Aryl O-Sulfamate Pharmacophore for Oncology and Women's Health.

Thomas MP, Potter BV. Thomas MP, et al. J Med Chem. 2015 Oct 8;58(19):7634-58. doi: 10.1021/acs.jmedchem.5b00386. Epub 2015 Jun 12. J Med Chem. 2015. PMID: 25992880 Free PMC article.

9

Targeted NF1 cancer therapeutics with multiple modes of action: small molecule hormone-like agents resembling the natural anticancer metabolite, 2-methoxyoestradiol.

Shen YC, Upadhyayula R, Cevallos S, Messick RJ, Hsia T, Leese MP, Jewett DM, Ferrer-Torres D, Roth TM, Dohle W, Potter BV, Barald KF. Shen YC, et al. Br J Cancer. 2015 Oct 20;113(8):1158-67. doi: 10.1038/bjc.2015.345. Epub 2015 Oct 13. Br J Cancer. 2015. PMID: 26461061 Free PMC article.

10

Quinazolinone-Based Anticancer Agents: Synthesis, Antiproliferative SAR, Antitubulin Activity, and Tubulin Co-crystal Structure.

Dohle W, Jourdan FL, Menchon G, Prota AE, Foster PA, Mannion P, Hamel E, Thomas MP, Kasprzyk PG, Ferrandis E, Steinmetz MO, Leese MP, Potter BVL. Dohle W, et al. Among authors: potter bvl. J Med Chem. 2018 Feb 8;61(3):1031-1044. doi: 10.1021/acs.jmedchem.7b01474. Epub 2018 Jan 8. J Med Chem. 2018. PMID: 29227648

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