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Page 1
New Insights into the Mechanism of Action of the Thienopyrimidine Antitubercular Prodrug TP053.
Chiarelli LR, Salina EG, Mori G, Azhikina T, Riabova O, Lepioshkin A, Grigorov A, Forbak M, Madacki J, Orena BS, Manfredi M, Gosetti F, Buzzi A, Degiacomi G, Sammartino JC, Marengo E, Korduláková J, Riccardi G, Mikušová K, Makarov V, Pasca MR. Chiarelli LR, et al. Among authors: kordulakova j. ACS Infect Dis. 2020 Feb 14;6(2):313-323. doi: 10.1021/acsinfecdis.9b00388. Epub 2019 Dec 2. ACS Infect Dis. 2020. PMID: 31729215
Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis.
Makarov V, Manina G, Mikusova K, Möllmann U, Ryabova O, Saint-Joanis B, Dhar N, Pasca MR, Buroni S, Lucarelli AP, Milano A, De Rossi E, Belanova M, Bobovska A, Dianiskova P, Kordulakova J, Sala C, Fullam E, Schneider P, McKinney JD, Brodin P, Christophe T, Waddell S, Butcher P, Albrethsen J, Rosenkrands I, Brosch R, Nandi V, Bharath S, Gaonkar S, Shandil RK, Balasubramanian V, Balganesh T, Tyagi S, Grosset J, Riccardi G, Cole ST. Makarov V, et al. Among authors: kordulakova j. Science. 2009 May 8;324(5928):801-4. doi: 10.1126/science.1171583. Epub 2009 Mar 19. Science. 2009. PMID: 19299584 Free PMC article.
The phosphatidyl-myo-inositol mannosyltransferase PimA is essential for Mycobacterium tuberculosis growth in vitro and in vivo.
Boldrin F, Ventura M, Degiacomi G, Ravishankar S, Sala C, Svetlikova Z, Ambady A, Dhar N, Kordulakova J, Zhang M, Serafini A, Vishwas KG, Kolly GS, Kumar N, Palù G, Guerin ME, Mikusova K, Cole ST, Manganelli R. Boldrin F, et al. Among authors: kordulakova j. J Bacteriol. 2014 Oct;196(19):3441-51. doi: 10.1128/JB.01346-13. Epub 2014 Jul 21. J Bacteriol. 2014. PMID: 25049093 Free PMC article.
Lead selection and characterization of antitubercular compounds using the Nested Chemical Library.
Sipos A, Pató J, Székely R, Hartkoorn RC, Kékesi L, Őrfi L, Szántai-Kis C, Mikušová K, Svetlíková Z, Korduláková J, Nagaraja V, Godbole AA, Bush N, Collin F, Maxwell A, Cole ST, Kéri G. Sipos A, et al. Among authors: kordulakova j. Tuberculosis (Edinb). 2015 Jun;95 Suppl 1:S200-6. doi: 10.1016/j.tube.2015.02.028. Epub 2015 Feb 28. Tuberculosis (Edinb). 2015. PMID: 25801335
DprE1 Is a Vulnerable Tuberculosis Drug Target Due to Its Cell Wall Localization.
Brecik M, Centárová I, Mukherjee R, Kolly GS, Huszár S, Bobovská A, Kilacsková E, Mokošová V, Svetlíková Z, Šarkan M, Neres J, Korduláková J, Cole ST, Mikušová K. Brecik M, et al. Among authors: kordulakova j. ACS Chem Biol. 2015 Jul 17;10(7):1631-6. doi: 10.1021/acschembio.5b00237. Epub 2015 Apr 29. ACS Chem Biol. 2015. PMID: 25906160
Design, synthesis and evaluation of new GEQ derivatives as inhibitors of InhA enzyme and Mycobacterium tuberculosis growth.
Chollet A, Mori G, Menendez C, Rodriguez F, Fabing I, Pasca MR, Madacki J, Korduláková J, Constant P, Quémard A, Bernardes-Génisson V, Lherbet C, Baltas M. Chollet A, et al. Among authors: kordulakova j. Eur J Med Chem. 2015 Aug 28;101:218-35. doi: 10.1016/j.ejmech.2015.06.035. Epub 2015 Jun 20. Eur J Med Chem. 2015. PMID: 26142487
Pyrrolidinone and pyrrolidine derivatives: Evaluation as inhibitors of InhA and Mycobacterium tuberculosis.
Matviiuk T, Madacki J, Mori G, Orena BS, Menendez C, Kysil A, André-Barrès C, Rodriguez F, Korduláková J, Mallet-Ladeira S, Voitenko Z, Pasca MR, Lherbet C, Baltas M. Matviiuk T, et al. Among authors: kordulakova j. Eur J Med Chem. 2016 Nov 10;123:462-475. doi: 10.1016/j.ejmech.2016.07.028. Epub 2016 Jul 16. Eur J Med Chem. 2016. PMID: 27490025
Identification of aminopyrimidine-sulfonamides as potent modulators of Wag31-mediated cell elongation in mycobacteria.
Singh V, Dhar N, Pató J, Kolly GS, Korduláková J, Forbak M, Evans JC, Székely R, Rybniker J, Palčeková Z, Zemanová J, Santi I, Signorino-Gelo F, Rodrigues L, Vocat A, Covarrubias AS, Rengifo MG, Johnsson K, Mowbray S, Buechler J, Delorme V, Brodin P, Knott GW, Aínsa JA, Warner DF, Kéri G, Mikušová K, McKinney JD, Cole ST, Mizrahi V, Hartkoorn RC. Singh V, et al. Among authors: kordulakova j. Mol Microbiol. 2017 Jan;103(1):13-25. doi: 10.1111/mmi.13535. Epub 2016 Oct 29. Mol Microbiol. 2017. PMID: 27677649 Free article.
58 results