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Context-dependent activation of SIRT3 is necessary for anchorage-independent survival and metastasis of ovarian cancer cells.
Kim YS, Gupta Vallur P, Jones VM, Worley BL, Shimko S, Shin DH, Crawford LC, Chen CW, Aird KM, Abraham T, Shepherd TG, Warrick JI, Lee NY, Phaeton R, Mythreye K, Hempel N. Kim YS, et al. Among authors: aird km. Oncogene. 2020 Feb;39(8):1619-1633. doi: 10.1038/s41388-019-1097-7. Epub 2019 Nov 13. Oncogene. 2020. PMID: 31723239 Free PMC article.
GPx3 supports ovarian cancer progression by manipulating the extracellular redox environment.
Worley BL, Kim YS, Mardini J, Zaman R, Leon KE, Vallur PG, Nduwumwami A, Warrick JI, Timmins PF, Kesterson JP, Phaëton R, Lee NY, Walter V, Endres L, Mythreye K, Aird KM, Hempel N. Worley BL, et al. Among authors: aird km. Redox Biol. 2019 Jul;25:101051. doi: 10.1016/j.redox.2018.11.009. Epub 2018 Nov 17. Redox Biol. 2019. PMID: 30509602 Free PMC article.
Suppression of p16 Induces mTORC1-Mediated Nucleotide Metabolic Reprogramming.
Buj R, Chen CW, Dahl ES, Leon KE, Kuskovsky R, Maglakelidze N, Navaratnarajah M, Zhang G, Doan MT, Jiang H, Zaleski M, Kutzler L, Lacko H, Lu Y, Mills GB, Gowda R, Robertson GP, Warrick JI, Herlyn M, Imamura Y, Kimball SR, DeGraff DJ, Snyder NW, Aird KM. Buj R, et al. Among authors: aird km. Cell Rep. 2019 Aug 20;28(8):1971-1980.e8. doi: 10.1016/j.celrep.2019.07.084. Cell Rep. 2019. PMID: 31433975 Free PMC article.
ATM inhibition drives metabolic adaptation via induction of macropinocytosis.
Huang Z, Chen CW, Buj R, Tangudu NK, Fang RS, Leon KE, Dahl ES, Varner EL, von Krusenstiern E, Cole AR, Snyder NW, Aird KM. Huang Z, et al. Among authors: aird km. J Cell Biol. 2023 Jan 2;222(1):e202007026. doi: 10.1083/jcb.202007026. Epub 2022 Nov 18. J Cell Biol. 2023. PMID: 36399181 Free PMC article.
GPX3 supports ovarian cancer tumor progression in vivo and promotes expression of GDF15.
Chang C, Cheng YY, Kamlapurkar S, White SR, Tang PW, Elhaw AT, Javed Z, Aird KM, Mythreye K, Phaëton R, Hempel N. Chang C, et al. Among authors: aird km. bioRxiv [Preprint]. 2024 Jan 29:2024.01.24.577037. doi: 10.1101/2024.01.24.577037. bioRxiv. 2024. Update in: Gynecol Oncol. 2024 Jun;185:8-16. doi: 10.1016/j.ygyno.2024.02.004. PMID: 38352432 Free PMC article. Updated. Preprint.
70 results