Woods HF - Search Results

1

Use of quinidine inhibition to define the role of the sparteine/debrisoquine cytochrome P450 in metoprolol oxidation by human liver microsomes.

Otton SV, Crewe HK, Lennard MS, Tucker GT, Woods HF. Otton SV, et al. Among authors: woods hf. J Pharmacol Exp Ther. 1988 Oct;247(1):242-7. J Pharmacol Exp Ther. 1988. PMID: 3171974

2

The demethylenation of methylenedioxymethamphetamine ("ecstasy") by debrisoquine hydroxylase (CYP2D6).

Tucker GT, Lennard MS, Ellis SW, Woods HF, Cho AK, Lin LY, Hiratsuka A, Schmitz DA, Chu TY. Tucker GT, et al. Among authors: woods hf. Biochem Pharmacol. 1994 Mar 29;47(7):1151-6. doi: 10.1016/0006-2952(94)90386-7. Biochem Pharmacol. 1994. PMID: 7909223

3

Differential stereoselective metabolism of metoprolol in extensive and poor debrisoquin metabolizers.

Lennard MS, Tucker GT, Silas JH, Freestone S, Ramsay LE, Woods HF. Lennard MS, et al. Among authors: woods hf. Clin Pharmacol Ther. 1983 Dec;34(6):732-7. doi: 10.1038/clpt.1983.242. Clin Pharmacol Ther. 1983. PMID: 6641087

4

Evidence for a dissociation in the control of sparteine, debrisoquine and metoprolol metabolism in Nigerians.

Lennard MS, Iyun AO, Jackson PR, Tucker GT, Woods HF. Lennard MS, et al. Among authors: woods hf. Pharmacogenetics. 1992 Apr;2(2):89-92. doi: 10.1097/00008571-199204000-00006. Pharmacogenetics. 1992. PMID: 1302046

5

Catalytic activities of human debrisoquine 4-hydroxylase cytochrome P450 (CYP2D6) expressed in yeast.

Ellis SW, Ching MS, Watson PF, Henderson CJ, Simula AP, Lennard MS, Tucker GT, Woods HF. Ellis SW, et al. Among authors: woods hf. Biochem Pharmacol. 1992 Aug 18;44(4):617-20. doi: 10.1016/0006-2952(92)90394-x. Biochem Pharmacol. 1992. PMID: 1510710

6

Effect of steroids on the cytochrome P4502D6-catalysed metabolism of metoprolol.

Pepper JM, Lennard MS, Tucker GT, Woods HF. Pepper JM, et al. Among authors: woods hf. Pharmacogenetics. 1991 Nov;1(2):119-22. doi: 10.1097/00008571-199111000-00012. Pharmacogenetics. 1991. PMID: 1844870 No abstract available.

7

The expression of human cytochrome P450IA1 in the yeast Saccharomyces cerevisiae.

Ching MS, Lennard MS, Tucker GT, Woods HF, Kelly DE, Kelly SL. Ching MS, et al. Among authors: woods hf. Biochem Pharmacol. 1991 Jul 25;42(4):753-8. doi: 10.1016/0006-2952(91)90032-z. Biochem Pharmacol. 1991. PMID: 1867632

8

Assessment of the mouse as an experimental model for studying polymorphic oxidation of the sparteine/debrisoquine type.

Adams M, Lennard MS, Otton SV, Tucker GT, Woods HF. Adams M, et al. Among authors: woods hf. Biochem Pharmacol. 1991 Jul 25;42(4):947-9. doi: 10.1016/0006-2952(91)90057-c. Biochem Pharmacol. 1991. PMID: 1867648 No abstract available.

9

Propranolol oxidation by human liver microsomes--the use of cumene hydroperoxide to probe isoenzyme specificity and regio- and stereoselectivity.

Otton SV, Gillam EM, Lennard MS, Tucker GT, Woods HF. Otton SV, et al. Among authors: woods hf. Br J Clin Pharmacol. 1990 Nov;30(5):751-60. doi: 10.1111/j.1365-2125.1990.tb03846.x. Br J Clin Pharmacol. 1990. PMID: 2271375 Free PMC article.

10

Inhibition of lignocaine metabolism by beta-adrenoceptor antagonists in rat and human liver microsomes.

al-Asady SA, Black GL, Lennard MS, Tucker GT, Woods HF. al-Asady SA, et al. Among authors: woods hf. Xenobiotica. 1989 Sep;19(9):929-44. doi: 10.3109/00498258909043152. Xenobiotica. 1989. PMID: 2573201

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