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Identification of Diketopiperazine-Containing 2-Anilinobenzamides as Potent Sirtuin 2 (SIRT2)-Selective Inhibitors Targeting the "Selectivity Pocket", Substrate-Binding Site, and NAD+-Binding Site.
Mellini P, Itoh Y, Elboray EE, Tsumoto H, Li Y, Suzuki M, Takahashi Y, Tojo T, Kurohara T, Miyake Y, Miura Y, Kitao Y, Kotoku M, Iida T, Suzuki T. Mellini P, et al. Among authors: takahashi y. J Med Chem. 2019 Jun 27;62(12):5844-5862. doi: 10.1021/acs.jmedchem.9b00255. Epub 2019 Jun 12. J Med Chem. 2019. PMID: 31144814
Identification of Potent and Selective Inhibitors of Fat Mass Obesity-Associated Protein Using a Fragment-Merging Approach.
Prakash M, Itoh Y, Fujiwara Y, Takahashi Y, Takada Y, Mellini P, Elboray EE, Terao M, Yamashita Y, Yamamoto C, Yamaguchi T, Kotoku M, Kitao Y, Singh R, Roy R, Obika S, Oba M, Wang DO, Suzuki T. Prakash M, et al. Among authors: takahashi y. J Med Chem. 2021 Nov 11;64(21):15810-15824. doi: 10.1021/acs.jmedchem.1c01107. Epub 2021 Nov 3. J Med Chem. 2021. PMID: 34727689
Identification of Proteolysis Targeting Chimeras (PROTACs) for Lysine Demethylase 5 and Their Neurite Outgrowth-Promoting Activity.
Iida T, Itoh Y, Takahashi Y, Miyake Y, Zamani F, Yamashita Y, Takada Y, Akiyama T, Ibaraki J, Okuda K, Tokuda Y, Nishimura T, Hidaka K, Mori H, Oba M, Suzuki T. Iida T, et al. Among authors: takahashi y. Chem Pharm Bull (Tokyo). 2024;72(7):638-647. doi: 10.1248/cpb.c23-00026. Chem Pharm Bull (Tokyo). 2024. PMID: 38945940 Free article.
Adjuvant Chemotherapy After Resection of Localized Pancreatic Adenocarcinoma Following Preoperative FOLFIRINOX.
Stoop TF, Sugawara T, Oba A, Feld IM, van Roessel S, van Veldhuisen E, Wu YHA, Nishino J, Ali M, Alseidi A, Sauvanet A, Mirabella A, Sa Cunha A, Kokkola A, Groot Koerkamp B, Pietrasz D, Kleive D, Butturini G, Malleo G, van Laarhoven HWM, Frigerio I, Dembinski J, He J, Gagnière J, Kleeff J, Ramia JM, Roberts KJ, Labori KJ, Marino MV, Falconi M, B Mortensen M, Lesurtel M, Bonds M, Chatzizacharias N, Strobel O, Turrini O, Griffin O, Franklin O, Pfeiffer P, Schulick RD, Salvia R, de Wilde RF, Dokmak S, Rodriguez Franco S, Augustinus S, Burgdorf SK, Crippa S, Hackert T, Tarvainen T, Burns WR, Messersmith W, Wilmink JW, Burkhart RA, Del Chiaro M, Besselink MG; Scientific Committee of the European-African Hepato-Pancreato-Biliary Association (E-AHPBA) and International Collaboration on Advanced Pancreatic Cancer. Stoop TF, et al. JAMA Oncol. 2025 Jan 23. doi: 10.1001/jamaoncol.2024.5917. Online ahead of print. JAMA Oncol. 2025. PMID: 39847363
Confined nanopore electrochemistry: general discussion.
Actis P, Aoki K, Baker LA, Ding Z, Ewing AG, Fu KX, Gooding JJ, Huang J, Kanoufi F, Kasianowicz JJ, Kim M, Kranz C, Kuttner C, Li F, Liu L, Liu W, Lu J, Lu SM, McKelvey K, Mount AR, Ren H, Shao Y, Takahashi Y, Tan S, Tang J, Wang H, Wang K, Wang L, Wang W, Xia F, Xiong T, Ying YL, Zhai Y, Zhao Z, Zhou Y. Actis P, et al. Among authors: takahashi y. Faraday Discuss. 2025 Jan 23. doi: 10.1039/d4fd90067g. Online ahead of print. Faraday Discuss. 2025. PMID: 39846715 No abstract available.
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