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Sustainable Syntheses of (-)-Jerantinines A & E and Structural Characterisation of the Jerantinine-Tubulin Complex at the Colchicine Binding Site.
Smedley CJ, Stanley PA, Qazzaz ME, Prota AE, Olieric N, Collins H, Eastman H, Barrow AS, Lim KH, Kam TS, Smith BJ, Duivenvoorden HM, Parker BS, Bradshaw TD, Steinmetz MO, Moses JE. Smedley CJ, et al. Sci Rep. 2018 Jul 13;8(1):10617. doi: 10.1038/s41598-018-28880-2. Sci Rep. 2018. PMID: 30006510 Free PMC article.
The growing applications of SuFEx click chemistry.
Barrow AS , Smedley CJ , Zheng Q , Li S , Dong J , Moses JE . Barrow AS , et al. Among authors: smedley cj. Chem Soc Rev. 2019 Aug 27;48(17):4731-4758. doi: 10.1039/c8cs00960k. Chem Soc Rev. 2019. PMID: 31364998 Review.
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase.
Zheng Q, Woehl JL, Kitamura S, Santos-Martins D, Smedley CJ, Li G, Forli S, Moses JE, Wolan DW, Sharpless KB. Zheng Q, et al. Among authors: smedley cj. Proc Natl Acad Sci U S A. 2019 Sep 17;116(38):18808-18814. doi: 10.1073/pnas.1909972116. Epub 2019 Sep 4. Proc Natl Acad Sci U S A. 2019. PMID: 31484779 Free PMC article.
Accelerated SuFEx Click Chemistry For Modular Synthesis.
Smedley CJ, Homer JA, Gialelis TL, Barrow AS, Koelln RA, Moses JE. Smedley CJ, et al. Angew Chem Int Ed Engl. 2022 Jan 21;61(4):e202112375. doi: 10.1002/anie.202112375. Epub 2021 Dec 7. Angew Chem Int Ed Engl. 2022. PMID: 34755436 Free PMC article.
17 results