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Diversity Oriented Clicking (DOC): Divergent Synthesis of SuFExable Pharmacophores from 2-Substituted-Alkynyl-1-Sulfonyl Fluoride (SASF) Hubs.
Smedley CJ, Li G, Barrow AS, Gialelis TL, Giel MC, Ottonello A, Cheng Y, Kitamura S, Wolan DW, Sharpless KB, Moses JE. Smedley CJ, et al. Among authors: giel mc. Angew Chem Int Ed Engl. 2020 Jul 20;59(30):12460-12469. doi: 10.1002/anie.202003219. Epub 2020 Jun 4. Angew Chem Int Ed Engl. 2020. PMID: 32301265 Free PMC article.
Diversity oriented clicking delivers β-substituted alkenyl sulfonyl fluorides as covalent human neutrophil elastase inhibitors.
Cheng Y, Li G, Smedley CJ, Giel MC, Kitamura S, Woehl JL, Bianco G, Forli S, Homer JA, Cappiello JR, Wolan DW, Moses JE, Sharpless KB. Cheng Y, et al. Among authors: giel mc. Proc Natl Acad Sci U S A. 2022 Sep 13;119(37):e2208540119. doi: 10.1073/pnas.2208540119. Epub 2022 Sep 7. Proc Natl Acad Sci U S A. 2022. PMID: 36070343 Free PMC article.
Novel Formulation of Undecylenic Acid induces Tumor Cell Apoptosis.
Day ZI, Mayfosh AJ, Giel MC, Hong Y, Williams SA, Santavanond JP, Rau TF, Poon IK, Hulett MD. Day ZI, et al. Among authors: giel mc. Int J Mol Sci. 2022 Nov 16;23(22):14170. doi: 10.3390/ijms232214170. Int J Mol Sci. 2022. PMID: 36430646 Free PMC article.
12 results