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635 results

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Page 1
Relationship between alirocumab, PCSK9, and LDL-C levels in four phase 3 ODYSSEY trials using 75 and 150 mg doses.
Robinson JG, Farnier M, Kastelein JJP, Roth EM, Taskinen MR, Colhoun HM, Brunet A, DiCioccio AT, Lecorps G, Pordy R, Baccara-Dinet MT, Cannon CP. Robinson JG, et al. Among authors: brunet a. J Clin Lipidol. 2019 Nov-Dec;13(6):979-988.e10. doi: 10.1016/j.jacl.2019.10.004. Epub 2019 Oct 14. J Clin Lipidol. 2019. PMID: 31708410 Free article. Clinical Trial.
Relationship Between Low-Density Lipoprotein Cholesterol, Free Proprotein Convertase Subtilisin/Kexin Type 9, and Alirocumab Levels After Different Lipid-Lowering Strategies.
Rey J, Poitiers F, Paehler T, Brunet A, DiCioccio AT, Cannon CP, Surks HK, Pinquier JL, Hanotin C, Sasiela WJ. Rey J, et al. Among authors: brunet a. J Am Heart Assoc. 2016 Jun 10;5(6):e003323. doi: 10.1161/JAHA.116.003323. J Am Heart Assoc. 2016. PMID: 27287699 Free PMC article. Clinical Trial.
Antidrug Antibodies in Patients Treated with Alirocumab.
Roth EM, Goldberg AC, Catapano AL, Torri A, Yancopoulos GD, Stahl N, Brunet A, Lecorps G, Colhoun HM. Roth EM, et al. Among authors: brunet a. N Engl J Med. 2017 Apr 20;376(16):1589-90. doi: 10.1056/NEJMc1616623. Epub 2017 Mar 17. N Engl J Med. 2017. PMID: 28304229 Free article. No abstract available.
Population Pharmacokinetic Analysis of Alirocumab in Healthy Volunteers or Hypercholesterolemic Subjects Using a Michaelis-Menten Approximation of a Target-Mediated Drug Disposition Model-Support for a Biologics License Application Submission: Part I.
Martinez JM, Brunet A, Hurbin F, DiCioccio AT, Rauch C, Fabre D. Martinez JM, et al. Among authors: brunet a. Clin Pharmacokinet. 2019 Jan;58(1):101-113. doi: 10.1007/s40262-018-0669-y. Clin Pharmacokinet. 2019. PMID: 29725996 Free PMC article. Clinical Trial.
Corrigendum to PCSK9 inhibition with alirocumab in pediatric patients with heterozygous familial hypercholesterolemia: The ODYSSEY KIDS study Volume 14, Issue 3, May-June 2020, Pages 322-330.e5.
Daniels S, Caprio S, Chaudhari U, Manvelian G, Baccara-Dinet MT, Brunet A, Scemama M, Loizeau V, Bruckert E. Daniels S, et al. Among authors: brunet a. J Clin Lipidol. 2020 Sep-Oct;14(5):741. doi: 10.1016/j.jacl.2020.08.011. J Clin Lipidol. 2020. PMID: 33138961 Free article. No abstract available.
A randomized study of the relative pharmacokinetics, pharmacodynamics, and safety of alirocumab, a fully human monoclonal antibody to PCSK9, after single subcutaneous administration at three different injection sites in healthy subjects.
Lunven C, Paehler T, Poitiers F, Brunet A, Rey J, Hanotin C, Sasiela WJ. Lunven C, et al. Among authors: brunet a. Cardiovasc Ther. 2014 Dec;32(6):297-301. doi: 10.1111/1755-5922.12093. Cardiovasc Ther. 2014. PMID: 25256660 Free PMC article. Clinical Trial.
Population Pharmacokinetic/Pharmacodynamic Analysis of Alirocumab in Healthy Volunteers or Hypercholesterolemic Subjects Using an Indirect Response Model to Predict Low-Density Lipoprotein Cholesterol Lowering: Support for a Biologics License Application Submission: Part II.
Nicolas X, Djebli N, Rauch C, Brunet A, Hurbin F, Martinez JM, Fabre D. Nicolas X, et al. Among authors: brunet a. Clin Pharmacokinet. 2019 Jan;58(1):115-130. doi: 10.1007/s40262-018-0670-5. Clin Pharmacokinet. 2019. PMID: 29725997 Free PMC article. Clinical Trial.
635 results