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Page 1
Comprehensive multiplexed immune profiling of the ductal carcinoma in situ immune microenvironment regarding subsequent ipsilateral invasive breast cancer risk.
Almekinders MM, Bismeijer T, Kumar T, Yang F, Thijssen B, van der Linden R, van Rooijen C, Vonk S, Sun B, Parra Cuentas ER, Wistuba II, Krishnamurthy S, Visser LL, Seignette IM, Hofland I, Sanders J, Broeks A, Love JK, Menegaz B, Wessels L, Thompson AM, de Visser KE, Hooijberg E, Lips E, Futreal A, Wesseling J; Grand Challenge PRECISION Consortium. Almekinders MM, et al. Among authors: seignette im. Br J Cancer. 2022 Oct;127(7):1201-1213. doi: 10.1038/s41416-022-01888-2. Epub 2022 Jun 29. Br J Cancer. 2022. PMID: 35768550 Free PMC article.
Neoadjuvant immunotherapy with nivolumab and ipilimumab induces major pathological responses in patients with head and neck squamous cell carcinoma.
Vos JL, Elbers JBW, Krijgsman O, Traets JJH, Qiao X, van der Leun AM, Lubeck Y, Seignette IM, Smit LA, Willems SM, van den Brekel MWM, Dirven R, Baris Karakullukcu M, Karssemakers L, Klop WMC, Lohuis PJFM, Schreuder WH, Smeele LE, van der Velden LA, Bing Tan I, Onderwater S, Jasperse B, Vogel WV, Al-Mamgani A, Keijser A, van der Noort V, Broeks A, Hooijberg E, Peeper DS, Schumacher TN, Blank CU, de Boer JP, Haanen JBAG, Zuur CL. Vos JL, et al. Among authors: seignette im. Nat Commun. 2021 Dec 22;12(1):7348. doi: 10.1038/s41467-021-26472-9. Nat Commun. 2021. PMID: 34937871 Free PMC article. Clinical Trial.
Karyotype evolution in response to chemoradiotherapy and upon recurrence of esophageal adenocarcinomas.
van der Sluis K, van Sandick JW, Koemans WJ, van den Bosch T, Broeks A, Peters D, Seignette IM, Rausch CR, van Dijk E, Snaebjornsson P, van den Berg JG, van Grieken NCT, Ylstra B, Carvalho B, Miedema DM, Kodach LL. van der Sluis K, et al. Among authors: seignette im. Cell Rep. 2024 Nov 26;43(11):114981. doi: 10.1016/j.celrep.2024.114981. Epub 2024 Nov 12. Cell Rep. 2024. PMID: 39535918 Free article.
Diversity of the immune microenvironment and response to checkpoint inhibitor immunotherapy in mucosal melanoma.
Vos JL, Traets JJ, Qiao X, Seignette IM, Peters D, Wouters MW, Hooijberg E, Broeks A, van der Wal JE, Karakullukcu MB, Klop WMC, Navran A, van Beurden M, Brouwer OR, Morris LG, van Poelgeest MI, Kapiteijn E, Haanen JB, Blank CU, Zuur CL. Vos JL, et al. Among authors: seignette im. JCI Insight. 2024 Nov 8;9(21):e179982. doi: 10.1172/jci.insight.179982. JCI Insight. 2024. PMID: 39513365 Free PMC article.
Platinum-Based Chemotherapy Induces Opposing Effects on Immunotherapy Response-Related Spatial and Stromal Biomarkers in the Bladder Cancer Microenvironment.
Chelushkin MA, van Dorp J, van Wilpe S, Seignette IM, Mellema JJ, Alkemade M, Gil-Jimenez A, Peters D, Brugman W, Stockem CF, Hooijberg E, Broeks A, van Rhijn BWG, Mertens LS, van der Heijden AG, Mehra N, van Montfoort ML, Wessels LFA, Vis DJ, van der Heijden MS. Chelushkin MA, et al. Among authors: seignette im. Clin Cancer Res. 2024 Sep 13;30(18):4227-4239. doi: 10.1158/1078-0432.CCR-24-0724. Clin Cancer Res. 2024. PMID: 39047168
Size and depth of residual tumor after neoadjuvant chemoradiotherapy in rectal cancer - implications for the development of new imaging modalities for response assessment.
van der Stel SD, van den Berg JG, Snaebjornsson P, Seignette IM, Witteveen M, Grotenhuis BA, Beets GL, Post AL, Ruers TJM. van der Stel SD, et al. Among authors: seignette im. Front Oncol. 2023 Sep 5;13:1209732. doi: 10.3389/fonc.2023.1209732. eCollection 2023. Front Oncol. 2023. PMID: 37736547 Free PMC article.
Atezolizumab With or Without Radiotherapy for Advanced Squamous Cell Carcinoma of the Penis (The PERICLES Study): A Phase II Trial.
de Vries HM, Rafael TS, Gil-Jimenez A, de Feijter JM, Bekers E, van der Laan E, Lopez-Yurda M, Hooijberg E, Broeks A, Peters D, Seignette IM, Pos FJ, Horenblas S, van Rhijn BWG, Jordanova ES, Brouwer OR, Schaake E, van der Heijden MS. de Vries HM, et al. Among authors: seignette im. J Clin Oncol. 2023 Nov 1;41(31):4872-4880. doi: 10.1200/JCO.22.02894. Epub 2023 Jul 24. J Clin Oncol. 2023. PMID: 37487169 Clinical Trial.
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