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Autophagy supports generation of cells with high CD44 expression via modulation of oxidative stress and Parkin-mediated mitochondrial clearance.
Whelan KA, Chandramouleeswaran PM, Tanaka K, Natsuizaka M, Guha M, Srinivasan S, Darling DS, Kita Y, Natsugoe S, Winkler JD, Klein-Szanto AJ, Amaravadi RK, Avadhani NG, Rustgi AK, Nakagawa H. Whelan KA, et al. Among authors: guha m. Oncogene. 2017 Aug 24;36(34):4843-4858. doi: 10.1038/onc.2017.102. Epub 2017 Apr 17. Oncogene. 2017. PMID: 28414310 Free PMC article.
ALDH2 modulates autophagy flux to regulate acetaldehyde-mediated toxicity thresholds.
Tanaka K, Whelan KA, Chandramouleeswaran PM, Kagawa S, Rustgi SL, Noguchi C, Guha M, Srinivasan S, Amanuma Y, Ohashi S, Muto M, Klein-Szanto AJ, Noguchi E, Avadhani NG, Nakagawa H. Tanaka K, et al. Among authors: guha m. Am J Cancer Res. 2016 Mar 15;6(4):781-96. eCollection 2016. Am J Cancer Res. 2016. PMID: 27186430 Free PMC article.
HnRNPA2 is a novel histone acetyltransferase that mediates mitochondrial stress-induced nuclear gene expression.
Guha M, Srinivasan S, Guja K, Mejia E, Garcia-Diaz M, Johnson FB, Ruthel G, Kaufman BA, Rappaport EF, Glineburg MR, Fang JK, Klein-Szanto AJ, Klein Szanto A, Nakagawa H, Basha J, Kundu T, Avadhani NG. Guha M, et al. Cell Discov. 2016 Dec 6;2:16045. doi: 10.1038/celldisc.2016.45. eCollection 2016. Cell Discov. 2016. PMID: 27990297 Free PMC article.
Mitochondrial dysfunction and mitochondrial dynamics-The cancer connection.
Srinivasan S, Guha M, Kashina A, Avadhani NG. Srinivasan S, et al. Among authors: guha m. Biochim Biophys Acta Bioenerg. 2017 Aug;1858(8):602-614. doi: 10.1016/j.bbabio.2017.01.004. Epub 2017 Jan 16. Biochim Biophys Acta Bioenerg. 2017. PMID: 28104365 Free PMC article. Review.
Autophagy mitigates ethanol-induced mitochondrial dysfunction and oxidative stress in esophageal keratinocytes.
Chandramouleeswaran PM, Guha M, Shimonosono M, Whelan KA, Maekawa H, Sachdeva UM, Ruthel G, Mukherjee S, Engel N, Gonzalez MV, Garifallou J, Ohashi S, Klein-Szanto AJ, Mesaros CA, Blair IA, Pellegrino da Silva R, Hakonarson H, Noguchi E, Baur JA, Nakagawa H. Chandramouleeswaran PM, et al. Among authors: guha m. PLoS One. 2020 Sep 23;15(9):e0239625. doi: 10.1371/journal.pone.0239625. eCollection 2020. PLoS One. 2020. PMID: 32966340 Free PMC article.
220 results