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189 results

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Esophageal 3D organoids of MPV17-/- mouse model of mitochondrial DNA depletion show epithelial cell plasticity and telomere attrition.
Guha M, Srinivasan S, Sheehan MM, Kijima T, Ruthel G, Whelan K, Tanaka K, Klein-Szanto A, Chandramouleeswaran PM, Nakagawa H, Avadhani NG. Guha M, et al. Among authors: avadhani ng. Oncotarget. 2019 Oct 22;10(58):6245-6259. doi: 10.18632/oncotarget.27264. eCollection 2019 Oct 22. Oncotarget. 2019. PMID: 31692873 Free PMC article.
ALDH2 modulates autophagy flux to regulate acetaldehyde-mediated toxicity thresholds.
Tanaka K, Whelan KA, Chandramouleeswaran PM, Kagawa S, Rustgi SL, Noguchi C, Guha M, Srinivasan S, Amanuma Y, Ohashi S, Muto M, Klein-Szanto AJ, Noguchi E, Avadhani NG, Nakagawa H. Tanaka K, et al. Among authors: avadhani ng. Am J Cancer Res. 2016 Mar 15;6(4):781-96. eCollection 2016. Am J Cancer Res. 2016. PMID: 27186430 Free PMC article.
HnRNPA2 is a novel histone acetyltransferase that mediates mitochondrial stress-induced nuclear gene expression.
Guha M, Srinivasan S, Guja K, Mejia E, Garcia-Diaz M, Johnson FB, Ruthel G, Kaufman BA, Rappaport EF, Glineburg MR, Fang JK, Klein-Szanto AJ, Klein Szanto A, Nakagawa H, Basha J, Kundu T, Avadhani NG. Guha M, et al. Among authors: avadhani ng. Cell Discov. 2016 Dec 6;2:16045. doi: 10.1038/celldisc.2016.45. eCollection 2016. Cell Discov. 2016. PMID: 27990297 Free PMC article.
Three-Dimensional Organoids Reveal Therapy Resistance of Esophageal and Oropharyngeal Squamous Cell Carcinoma Cells.
Kijima T, Nakagawa H, Shimonosono M, Chandramouleeswaran PM, Hara T, Sahu V, Kasagi Y, Kikuchi O, Tanaka K, Giroux V, Muir AB, Whelan KA, Ohashi S, Naganuma S, Klein-Szanto AJ, Shinden Y, Sasaki K, Omoto I, Kita Y, Muto M, Bass AJ, Diehl JA, Ginsberg GG, Doki Y, Mori M, Uchikado Y, Arigami T, Avadhani NG, Basu D, Rustgi AK, Natsugoe S. Kijima T, et al. Among authors: avadhani ng. Cell Mol Gastroenterol Hepatol. 2018 Sep 14;7(1):73-91. doi: 10.1016/j.jcmgh.2018.09.003. eCollection 2019. Cell Mol Gastroenterol Hepatol. 2018. PMID: 30510992 Free PMC article.
Autophagy supports generation of cells with high CD44 expression via modulation of oxidative stress and Parkin-mediated mitochondrial clearance.
Whelan KA, Chandramouleeswaran PM, Tanaka K, Natsuizaka M, Guha M, Srinivasan S, Darling DS, Kita Y, Natsugoe S, Winkler JD, Klein-Szanto AJ, Amaravadi RK, Avadhani NG, Rustgi AK, Nakagawa H. Whelan KA, et al. Among authors: avadhani ng. Oncogene. 2017 Aug 24;36(34):4843-4858. doi: 10.1038/onc.2017.102. Epub 2017 Apr 17. Oncogene. 2017. PMID: 28414310 Free PMC article.
189 results