Wirtz S - Search Results

1

STAT3 activation through IL-6/IL-11 in cancer-associated fibroblasts promotes colorectal tumour development and correlates with poor prognosis.

Heichler C, Scheibe K, Schmied A, Geppert CI, Schmid B, Wirtz S, Thoma OM, Kramer V, Waldner MJ, Büttner C, Farin HF, Pešić M, Knieling F, Merkel S, Grüneboom A, Gunzer M, Grützmann R, Rose-John S, Koralov SB, Kollias G, Vieth M, Hartmann A, Greten FR, Neurath MF, Neufert C. Heichler C, et al. Among authors: wirtz s. Gut. 2020 Jul;69(7):1269-1282. doi: 10.1136/gutjnl-2019-319200. Epub 2019 Nov 4. Gut. 2020. PMID: 31685519

2

Cutting edge: chronic intestinal inflammation in STAT-4 transgenic mice: characterization of disease and adoptive transfer by TNF- plus IFN-gamma-producing CD4+ T cells that respond to bacterial antigens.

Wirtz S, Finotto S, Kanzler S, Lohse AW, Blessing M, Lehr HA, Galle PR, Neurath MF. Wirtz S, et al. J Immunol. 1999 Feb 15;162(4):1884-8. J Immunol. 1999. PMID: 9973454

3

Efficient gene delivery to the inflamed colon by local administration of recombinant adenoviruses with normal or modified fibre structure.

Wirtz S, Galle PR, Neurath MF. Wirtz S, et al. Gut. 1999 Jun;44(6):800-7. doi: 10.1136/gut.44.6.800. Gut. 1999. PMID: 10323880 Free PMC article.

4

Constitutive and inducible in vivo protein-DNA interactions at the tumor necrosis factor-alpha promoter in primary human T lymphocytes.

Becker C, Barbulescu K, Wirtz S, Meyer zum Büschenfelde KH, Pettersson S, Neurath MF. Becker C, et al. Among authors: wirtz s. Gene Expr. 1999;8(2):115-27. Gene Expr. 1999. PMID: 10551799 Free PMC article.

5

Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: evidence in crohn disease and experimental colitis in vivo.

Atreya R, Mudter J, Finotto S, Müllberg J, Jostock T, Wirtz S, Schütz M, Bartsch B, Holtmann M, Becker C, Strand D, Czaja J, Schlaak JF, Lehr HA, Autschbach F, Schürmann G, Nishimoto N, Yoshizaki K, Ito H, Kishimoto T, Galle PR, Rose-John S, Neurath MF. Atreya R, et al. Among authors: wirtz s. Nat Med. 2000 May;6(5):583-8. doi: 10.1038/75068. Nat Med. 2000. PMID: 10802717

6

Animal models of intestinal inflammation: new insights into the molecular pathogenesis and immunotherapy of inflammatory bowel disease.

Wirtz S, Neurath MF. Wirtz S, et al. Int J Colorectal Dis. 2000 Jun;15(3):144-60. doi: 10.1007/s003840000227. Int J Colorectal Dis. 2000. PMID: 10954186 Review.

7

Regulation of IL-12 p40 promoter activity in primary human monocytes: roles of NF-kappaB, CCAAT/enhancer-binding protein beta, and PU.1 and identification of a novel repressor element (GA-12) that responds to IL-4 and prostaglandin E(2).

Becker C, Wirtz S, Ma X, Blessing M, Galle PR, Neurath MF. Becker C, et al. Among authors: wirtz s. J Immunol. 2001 Sep 1;167(5):2608-18. doi: 10.4049/jimmunol.167.5.2608. J Immunol. 2001. PMID: 11509602

8

Treatment of T cell-dependent experimental colitis in SCID mice by local administration of an adenovirus expressing IL-18 antisense mRNA.

Wirtz S, Becker C, Blumberg R, Galle PR, Neurath MF. Wirtz S, et al. J Immunol. 2002 Jan 1;168(1):411-20. doi: 10.4049/jimmunol.168.1.411. J Immunol. 2002. PMID: 11751987

9

A new model of chronic colitis in SCID mice induced by adoptive transfer of CD62L+ CD4+ T cells: insights into the regulatory role of interleukin-6 on apoptosis.

Mudter J, Wirtz S, Galle PR, Neurath MF. Mudter J, et al. Among authors: wirtz s. Pathobiology. 2002-2003;70(3):170-6. doi: 10.1159/000068150. Pathobiology. 2002. PMID: 12571422

10

Gene transfer approaches for the treatment of inflammatory bowel disease.

Wirtz S, Neurath MF. Wirtz S, et al. Gene Ther. 2003 May;10(10):854-60. doi: 10.1038/sj.gt.3302013. Gene Ther. 2003. PMID: 12732871 Review.

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