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Page 1
Identifying new lead structures to enhance tolerance towards drought stress via high-throughput screening giving crops a quantum of solace.
Frackenpohl J, Schneider L, Decker LJB, Dittgen J, Fenkl F, Fischer C, Franke J, Freigang J, Getachew R, Gonzalez Fernandez-Nino SM, Helmke H, Hills MJ, Hohmann S, Kleemann J, Kurowski K, Lange G, Luemmen P, Meyering N, Poree F, Schmutzler D, Wrede S. Frackenpohl J, et al. Among authors: hohmann s. Bioorg Med Chem. 2019 Dec 15;27(24):115142. doi: 10.1016/j.bmc.2019.115142. Epub 2019 Oct 19. Bioorg Med Chem. 2019. PMID: 31685332
Insecticidal heterolignans--tubuline polymerization inhibitors with activity against chewing pests.
Frackenpohl J, Adelt I, Antonicek H, Arnold C, Behrmann P, Blaha N, Böhmer J, Gutbrod O, Hanke R, Hohmann S, van Houtdreve M, Lösel P, Malsam O, Melchers M, Neufert V, Peschel E, Reckmann U, Schenke T, Thiesen HP, Velten R, Vogelsang K, Weiss HC. Frackenpohl J, et al. Among authors: hohmann s. Bioorg Med Chem. 2009 Jun 15;17(12):4160-84. doi: 10.1016/j.bmc.2009.01.042. Epub 2009 Jan 24. Bioorg Med Chem. 2009. PMID: 19223182
Abscisic acid agonists suitable for optimizing plant water use.
Roeder J, Liu J, Doch I, Ruschhaupt M, Christmann A, Grill E, Helmke H, Hohmann S, Lehr S, Frackenpohl J, Yang Z. Roeder J, et al. Among authors: hohmann s. Front Plant Sci. 2023 Jan 19;13:1071710. doi: 10.3389/fpls.2022.1071710. eCollection 2022. Front Plant Sci. 2023. PMID: 36743550 Free PMC article.
Design, synthesis and screening of herbicidal activity for new phenyl pyrazole-based protoporphyrinogen oxidase-inhibitors (PPO) overcoming resistance issues.
Mattison RL, Beffa R, Bojack G, Bollenbach-Wahl B, Dörnbrack C, Dorn N, Freigang J, Gatzweiler E, Getachew R, Hartfiel C, Heinemann I, Helmke H, Hohmann S, Jakobi H, Lange G, Lümmen P, Willms L, Frackenpohl J. Mattison RL, et al. Among authors: hohmann s. Pest Manag Sci. 2023 Jun;79(6):2264-2280. doi: 10.1002/ps.7425. Epub 2023 Mar 8. Pest Manag Sci. 2023. PMID: 36815643
Designing New Protoporphyrinogen Oxidase-Inhibitors Carrying Potential Side Chain Isosteres to Enhance Crop Safety and Spectrum of Activity.
Alnafta N, Beffa R, Bojack G, Bollenbach-Wahl B, Brant NZ, Dörnbrack C, Dorn N, Freigang J, Gatzweiler E, Getachew R, Hartfiel C, Heinemann I, Helmke H, Hohmann S, Jakobi H, Lange G, Lümmen P, Willms L, Frackenpohl J. Alnafta N, et al. Among authors: hohmann s. J Agric Food Chem. 2023 Nov 29;71(47):18270-18284. doi: 10.1021/acs.jafc.3c01420. Epub 2023 Jun 3. J Agric Food Chem. 2023. PMID: 37269295
Discovery and optimization of spirocyclic lactams that inhibit acyl-ACP thioesterase.
Asmus E, Barber DM, Bojack G, Bollenbach-Wahl B, Brown RW, Döller U, Freigang J, Gatzweiler E, Getachew R, Heinemann I, Hohmann S, Ko KY, Laber B, Lange G, Mattison RL, Minn K, Müller T, Petry T, Reingruber AM, Schmutzler D, Svejda A, Frackenpohl J. Asmus E, et al. Among authors: hohmann s. Pest Manag Sci. 2024 Feb 9. doi: 10.1002/ps.8015. Online ahead of print. Pest Manag Sci. 2024. PMID: 38334233
Synthesis and biological profile of 2,3-dihydro[1,3]thiazolo[4,5-b]pyridines, a novel class of acyl-ACP thioesterase inhibitors.
Frackenpohl J, Barber DM, Bojack G, Bollenbach-Wahl B, Braun R, Getachew R, Hohmann S, Ko KY, Kurowski K, Laber B, Mattison RL, Müller T, Reingruber AM, Schmutzler D, Svejda A. Frackenpohl J, et al. Among authors: hohmann s. Beilstein J Org Chem. 2024 Mar 1;20:540-551. doi: 10.3762/bjoc.20.46. eCollection 2024. Beilstein J Org Chem. 2024. PMID: 38440172 Free PMC article.
Synthesis and biological profile of substituted hexahydrofuro[3,4-b]furans, a novel class of bicyclic acyl-acyl carrier protein (ACP) thioesterase inhibitors.
Ahrens H, Barber DM, Bojack G, Bollenbach-Wahl B, Churchman L, Getachew R, Helmke H, Hohmann S, Laber B, Lange G, Rees S, Reingruber AM, Schmutzler D, Frackenpohl J. Ahrens H, et al. Among authors: hohmann s. Pest Manag Sci. 2024 Aug 6. doi: 10.1002/ps.8357. Online ahead of print. Pest Manag Sci. 2024. PMID: 39104300
Relationships of eating behaviors with psychopathology, brain maturation and genetic risk for obesity in an adolescent cohort study.
Yu X, Zhang Z, Herle M, Banaschewski T, Barker GJ, Bokde ALW, Flor H, Grigis A, Garavan H, Gowland P, Heinz A, Brühl R, Martinot JL, Martinot MP, Artiges E, Nees F, Orfanos DP, Lemaître H, Paus T, Poustka L, Hohmann S, Holz N, Bäuchl C, Smolka MN, Vaidya N, Walter H, Whelan R, Schmidt U, Schumann G, Desrivières S; IMAGEN consortium. Yu X, et al. Among authors: hohmann s. Nat Ment Health. 2025;3(1):58-70. doi: 10.1038/s44220-024-00354-7. Epub 2025 Jan 10. Nat Ment Health. 2025. PMID: 39811626 Free PMC article.
Genome-wide association study unravels mechanisms of brain glymphatic activity.
Huang SY, Ge YJ, Ren P, Wu BS, Gong W, Du J, Chen SD, Kang JJ, Ma Q, Bokde ALW, Desrivières S, Garavan H, Grigis A, Lemaitre H, Smolka MN, Hohmann S; IMAGEN Consortium; Feng JF, Zhang YR, Cheng W, Yu JT. Huang SY, et al. Among authors: hohmann s. Nat Commun. 2025 Jan 13;16(1):626. doi: 10.1038/s41467-024-55706-9. Nat Commun. 2025. PMID: 39805841 Free PMC article.
585 results