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An in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patients.
Spina CA, Anderson J, Archin NM, Bosque A, Chan J, Famiglietti M, Greene WC, Kashuba A, Lewin SR, Margolis DM, Mau M, Ruelas D, Saleh S, Shirakawa K, Siliciano RF, Singhania A, Soto PC, Terry VH, Verdin E, Woelk C, Wooden S, Xing S, Planelles V. Spina CA, et al. Among authors: bosque a. PLoS Pathog. 2013;9(12):e1003834. doi: 10.1371/journal.ppat.1003834. Epub 2013 Dec 26. PLoS Pathog. 2013. PMID: 24385908 Free PMC article.
Modeling HIV-1 Latency in Primary T Cells Using a Replication-Competent Virus.
Martins LJ, Bonczkowski P, Spivak AM, De Spiegelaere W, Novis CL, DePaula-Silva AB, Malatinkova E, Trypsteen W, Bosque A, Vanderkerckhove L, Planelles V. Martins LJ, et al. Among authors: bosque a. AIDS Res Hum Retroviruses. 2016 Feb;32(2):187-93. doi: 10.1089/aid.2015.0106. Epub 2015 Jul 14. AIDS Res Hum Retroviruses. 2016. PMID: 26171776 Free PMC article.
BIRC2/cIAP1 Is a Negative Regulator of HIV-1 Transcription and Can Be Targeted by Smac Mimetics to Promote Reversal of Viral Latency.
Pache L, Dutra MS, Spivak AM, Marlett JM, Murry JP, Hwang Y, Maestre AM, Manganaro L, Vamos M, Teriete P, Martins LJ, König R, Simon V, Bosque A, Fernandez-Sesma A, Cosford ND, Bushman FD, Young JA, Planelles V, Chanda SK. Pache L, et al. Among authors: bosque a. Cell Host Microbe. 2015 Sep 9;18(3):345-53. doi: 10.1016/j.chom.2015.08.009. Cell Host Microbe. 2015. PMID: 26355217 Free PMC article.
Transcriptomic Analysis Implicates the p53 Signaling Pathway in the Establishment of HIV-1 Latency in Central Memory CD4 T Cells in an In Vitro Model.
White CH, Moesker B, Beliakova-Bethell N, Martins LJ, Spina CA, Margolis DM, Richman DD, Planelles V, Bosque A, Woelk CH. White CH, et al. Among authors: bosque a. PLoS Pathog. 2016 Nov 29;12(11):e1006026. doi: 10.1371/journal.ppat.1006026. eCollection 2016 Nov. PLoS Pathog. 2016. PMID: 27898737 Free PMC article.
96 results