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The neuroprotective effects of SIRT1 in mice carrying the APP/PS1 double-transgenic mutation and in SH-SY5Y cells over-expressing human APP670/671 may involve elevated levels of α7 nicotinic acetylcholine receptors.
Cao K, Dong YT, Xiang J, Xu Y, Li Y, Song H, Yu WF, Qi XL, Guan ZZ. Cao K, et al. Among authors: song h. Aging (Albany NY). 2020 Jan 30;12(2):1792-1807. doi: 10.18632/aging.102713. Epub 2020 Jan 30. Aging (Albany NY). 2020. PMID: 32003755 Free PMC article.
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